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Details for Product No. ABIN393346

Growth Differentiation Factor 7 (GDF7) antibody

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Antigen
Synonyms BMP12, bmp12, gdf-7, gdf16, gdf16-A
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA
Pubmed 5 references available
Catalog no. ABIN393346
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen GDF7 (NP_878248, 361 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4F10
Isotype IgG2a kappa
Specificity GDF7 (NP_878248, 361 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name GDF7
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 46966 DA
Gene ID 12406
UniProt NP_878248
Research Area Neurology, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Butler, Dodd: "A role for BMP heterodimers in roof plate-mediated repulsion of commissural axons." in: Neuron, Vol. 38, Issue 3, pp. 389-401, 2003 (PubMed).

Mazerbourg, Sangkuhl, Luo et al.: "Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses." in: The Journal of biological chemistry, Vol. 280, Issue 37, pp. 32122-32, 2005 (PubMed).

Yeh, Lee: "Effects of cartilage-derived morphogenetic protein-3 on the expression of chondrogenic and osteoblastic markers in the pluripotent mesenchymal C3H10T1/2 cell line." in: Growth factors (Chur, Switzerland), Vol. 28, Issue 2, pp. 117-28, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Alternatives for antigen "Growth Differentiation Factor 7 (GDF7)", type "Antibodies"
Hosts (22), (16)
Reactivities (38), (12), (12), (12), (12), (12)
Applications (24), (21), (10), (3)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (6), (1)
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