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Protocadherin 1 (PCDH1) (AA 62-170) antibody

Details for Product No. ABIN393359, Supplier: Log in to see
Antigen
  • PC42
  • PCDH42
  • 2010005A06Rik
  • AI585920
  • PCDH-1
  • axpc
  • protocadherin-1
  • protocadherin 1
  • protocadherin-1-like
  • PCDH1
  • Pcdh1
  • pcdh1
  • LOC100856703
Epitope
AA 62-170
16
10
9
9
9
6
6
5
2
2
2
2
2
1
1
1
Reactivity
Human
86
25
21
2
1
1
1
1
1
Host
Mouse
63
25
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
5
5
4
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
64
38
31
26
20
13
12
9
3
3
1
1
1
Options
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Immunogen PCDH1 (NP_002578, 62 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 5D5
Isotype IgG1 kappa
Specificity PCDH1 (NP_002578, 62 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name PCDH1 (PCDH1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 111270 DA
Gene ID 12406
NCBI Accession NP_002578
Research Area Cell Structure, Neurology
Application Notes Western blot = 1:500-1000
Comment

Background: This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracelllular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Protocadherin 1 (PCDH1) (AA 62-170) antibody (ABIN393359) Immunofluorescence of monoclonal antibody to PCDH1 on A-431 cell (antibody concentrat...
Immunohistochemistry (IHC) image for anti-Protocadherin 1 (PCDH1) (AA 62-170) antibody (ABIN393359) anti-Protocadherin 1 (PCDH1) (AA 62-170) antibody (Image 2)
Background publications Koppelman, Meyers, Howard, Zheng, Hawkins, Ampleford, Xu, Koning, Bruinenberg, Nolte, van Diemen, Boezen, Timens, Whittaker, Stine, Barton, Holloway, Holgate, Graves, Martinez, van Oosterhout et al.: "Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness. ..." in: American journal of respiratory and critical care medicine, Vol. 180, Issue 10, pp. 929-35, 2009 (PubMed).

Otsuki, Ota, Nishikawa, Hayashi, Suzuki, Yamamoto, Wakamatsu, Kimura, Sakamoto, Hatano, Kawai, Ishii, Saito, Kojima, Sugiyama, Ono, Okano, Yoshikawa, Aotsuka, Sasaki, Hattori, Okumura, Nagai, Sugano et al.: "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. ..." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 12, Issue 2, pp. 117-26, 2005 (PubMed).

Rush, Moritz, Lee, Guo, Goss, Spek, Zhang, Zha, Polakiewicz, Comb: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Ballif, Villén, Beausoleil, Schwartz, Gygi: "Phosphoproteomic analysis of the developing mouse brain." in: Molecular & cellular proteomics : MCP, Vol. 3, Issue 11, pp. 1093-101, 2004 (PubMed).

Colland, Jacq, Trouplin, Mougin, Groizeleau, Hamburger, Meil, Wojcik, Legrain, Gauthier: "Functional proteomics mapping of a human signaling pathway." in: Genome research, Vol. 14, Issue 7, pp. 1324-32, 2004 (PubMed).