Cadherin 18, Type 2 (CDH18) (AA 467-577) antibody

Details for Product No. ABIN393369
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms B230220E17Rik, Cdh14l, CDH14, CDH14L, CDH24
Epitope
AA 467-577
(7), (7), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(44), (23), (17), (17), (17), (17), (17)
Host
Mouse
(38), (6)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(29), (21), (15), (10), (8), (8), (2)
Pubmed 5 references available
Quantity 0.1 mg
Options
Shipping to United States (Change)
Availability Available
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN393369
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen CDH18 (NP_004925, 467 a.a. ~ 577 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6F7
Isotype IgG2a kappa
Specificity CDH18 (NP_004925, 467 a.a. ~ 577 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name CDH18
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 88073 DA
Gene ID 12406
NCBI Accession NP_004925
Research Area Cell Structure, Neurology
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Cadherin 18, Type 2 (CDH18) (AA 467-577) antibody CDH18 monoclonal antibody (M01), clone 6F7 Western Blot analysis of CDH18 expression in HeLa on formalin-fixed paraffin-embedded human small Intestine (antibody concentration 3 µg/mL).
anti-Cadherin 18, Type 2 (CDH18) (AA 467-577) antibody (2) anti-Cadherin 18, Type 2 (CDH18) (AA 467-577) antibody (Image 2)
Background publications Shimoyama, Tsujimoto, Kitajima et al.: "Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins." in: The Biochemical journal, Vol. 349, Issue Pt 1, pp. 159-67, 2001 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Talmud, Drenos, Shah et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Yang, Yuan, Gao et al.: "[Expressions of cadherin molecules CDH18 and PCDH17 in human azoospermic testes]." in: Zhonghua nan ke xue = National journal of andrology, Vol. 15, Issue 12, pp. 1081-4, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Validation Images
Did you look for something else?
back to top