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Interleukin 17B (IL17B) (AA 23-123) antibody

Details for Product No. ABIN393370, Supplier: Login to see
Antigen
  • il-17b
  • il-20
  • zcyto7
  • IL17B
  • IL-17B
  • IL-20
  • NIRF
  • ZCYTO7
  • 1110006O16Rik
  • 1700006N07Rik
  • Zcyto7
Epitope
AA 23-123
15
13
13
9
9
5
3
3
2
2
2
2
2
2
1
1
1
1
Reactivity
Human
86
22
20
Host
Mouse
63
15
14
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
12
8
7
5
4
4
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
72
54
15
11
11
8
7
6
3
2
Supplier
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Immunogen IL17B (NP_055258, 23 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6G5
Isotype IgG2a kappa
Specificity IL17B (NP_055258, 23 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name IL17B (IL17B Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 20437 DA
Gene ID 12406
NCBI Accession NP_055258
Research Area Neurology, Cell Structure
Pathways
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Interleukin 17B (IL17B) (AA 23-123) antibody (ABIN393370) Detection limit for recombinant GST tagged IL17B is approximately 0.03 ng/mL as a cap...
Background publications Koskinen, Einarsdottir, Korponay-Szabo et al.: "Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations." in: Tissue antigens, Vol. 74, Issue 5, pp. 408-16, 2009 (PubMed).

Wang, Dong, Zhu et al.: "Expression profile of immune-associated genes in nasal polyps." in: The Annals of otology, rhinology, and laryngology, Vol. 115, Issue 6, pp. 450-6, 2006 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Ryan, Thornton, Brophy et al.: "Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1." in: Tissue antigens, Vol. 65, Issue 2, pp. 150-5, 2005 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).