Interleukin 17B (IL17B) (AA 23-123) antibody

Details for Product No. ABIN393370
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Antigen
Synonyms il-17b, il-20, zcyto7, IL17B, IL-17B, IL-20, NIRF, ZCYTO7, 1110006O16Rik, 1700006N07Rik, Zcyto7
Epitope
AA 23-123
(7), (6), (3), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(44), (15), (14), (12), (12), (12)
Host
Mouse
(35), (7), (4), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(7), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(36), (26), (10), (8), (7), (6), (4), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN393370
450.00 $
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Immunogen IL17B (NP_055258, 23 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 6G5
Isotype IgG2a kappa
Specificity IL17B (NP_055258, 23 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name IL17B
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 20437 DA
Gene ID 12406
NCBI Accession NP_055258
Research Area Neurology, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Interleukin 17B (IL17B) (AA 23-123) antibody Detection limit for recombinant GST tagged IL17B is approximately 0.03 ng/mL as a capture antibody.
Background publications Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Ryan, Thornton, Brophy et al.: "Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1." in: Tissue antigens, Vol. 65, Issue 2, pp. 150-5, 2005 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome...." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Wang, Dong, Zhu et al.: "Expression profile of immune-associated genes in nasal polyps." in: The Annals of otology, rhinology, and laryngology, Vol. 115, Issue 6, pp. 450-6, 2006 (PubMed).

Koskinen, Einarsdottir, Korponay-Szabo et al.: "Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations." in: Tissue antigens, Vol. 74, Issue 5, pp. 408-16, 2009 (PubMed).

Validation Images
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