Interleukin 17B (IL17B) antibody

Antigen: Interleukin 17B (IL17B)

Synonyms: IL-20, IL-17B, ZCYTO7, MGC138900, MGC138901, Zcyto7, 1110006O16Rik, 1700006N07Rik, il-20, il-17b, zcyto7, MGC89153, IL17B

Clonality: Monoclonal (6G5)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN393370

Additional Information

Alternative name: IL17B

Gene ID: 27190

UniProt: NP_055258

Immunogen: IL17B (NP_055258, 23 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a kappa

Clone: 6G5

Description: Other names: IL17B, IL20, ZCYTO7 interleukin 17B

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: IL17B (NP_055258, 23 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 20437 DA

Comments:

Background: The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Neurology, Cell Structure

Restrictions: For Research Use only

Images

Detection limit for recombinant GST tagged IL17B is approximately 0.03ng/ml as a capture antibody.

Publications

Product: Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Ryan, Thornton, Brophy et al.: "Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1." in: Tissue antigens, Vol. 65, Issue 2, pp. 150-5, 2005 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Wang, Dong, Zhu et al.: "Expression profile of immune-associated genes in nasal polyps." in: The Annals of otology, rhinology, and laryngology, Vol. 115, Issue 6, pp. 450-6, 2006 (PubMed).

Koskinen, Einarsdottir, Korponay-Szabo et al.: "Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations." in: Tissue antigens, Vol. 74, Issue 5, pp. 408-16, 2009 (PubMed).