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ADPGK antibody (ADP-Dependent Glucokinase) (AA 425-497)

Details for Product anti-ADPGK Antibody No. ABIN393388, Supplier: Login to see
Antigen
  • ADPGK
  • 2610017G09Rik
  • ADP-GK
  • Adp-gk
  • C77577
  • RGD1306103
Epitope
AA 425-497
5
4
3
3
2
2
2
2
1
1
Reactivity
Human
40
20
18
4
3
2
Host
Mouse
34
6
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
38
18
11
3
2
1
1
1
1
Supplier
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Immunogen ADPGK (NP_112574, 425 a.a. ~ 497 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1E4
Isotype IgG2a kappa
Specificity ADPGK (NP_112574, 425 a.a. ~ 497 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ADPGK (ADPGK Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 54089 DA
Gene ID 12406
NCBI Accession NP_112574
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Pathways
Application Notes Western blot = 1:500-1000
Comment

Background: ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ADPGK antibody (ADP-Dependent Glucokinase) (AA 425-497) (ABIN393388) Western Blot analysis of ADPGK expression in transfected 293T cell line by ADPGK mono...
Immunohistochemistry (IHC) image for anti-ADPGK antibody (ADP-Dependent Glucokinase) (AA 425-497) (ABIN393388) anti-ADP-Dependent Glucokinase (ADPGK) (AA 425-497) antibody (Image 2)
Background publications Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Cuesta-Muñoz, Tuomi, Cobo-Vuilleumier et al.: "Clinical heterogeneity in monogenic diabetes caused by mutations in the glucokinase gene (GCK-MODY)." in: Diabetes Care, Vol. 33, Issue 2, pp. 290-2, 2010 (PubMed).

Codner, Rocha, Deng et al.: "Mild fasting hyperglycemia in children: high rate of glucokinase mutations and some risk of developing type 1 diabetes mellitus." in: Pediatric diabetes, Vol. 10, Issue 6, pp. 382-8, 2009 (PubMed).

Lim, Hao, Shaw et al.: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).

Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).