ADP-Dependent Glucokinase (ADPGK) antibody

Details for Product No. ABIN393388
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

 
Antigen
Synonyms 2610017G09Rik, ADP-GK, Adp-gk, C77577, RGD1306103, ADPGK
Reactivity
Human
(28), (19), (17), (4), (3)
Host
Mouse
(25), (3)
Clonality (Clone)
Monoclonal ()
Application
Western Blotting (WB)
(28), (13), (5), (2), (1)
Pubmed 5 references available
Catalog no. ABIN393388
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen ADPGK (NP_112574, 425 a.a. ~ 497 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1E4
Isotype IgG2a kappa
Specificity ADPGK (NP_112574, 425 a.a. ~ 497 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ADPGK
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 54089 DA
Gene ID 12406
UniProt NP_112574
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-ADP-Dependent Glucokinase (ADPGK) antibody Western Blot analysis of ADPGK expression in transfected 293T cell line by ADPGK monoclonal antibody (M01), clone 1E4. Lane 1: ADPGK transfected lysate(54.1 KDa). Lane 2: Non-transfected lysate. Western blot analysis of ADPGK over-expressed 293 cell line, cotransfected with ADPGK Validated Chimera RNAi used as specificity and loading control.
anti-ADP-Dependent Glucokinase (ADPGK) antibody (2) anti-ADP-Dependent Glucokinase (ADPGK) antibody (Image 2)
Background publications Talmud, Drenos, Shah et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).

Lim, Hao, Shaw et al.: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).

Codner, Rocha, Deng et al.: "Mild fasting hyperglycemia in children: high rate of glucokinase mutations and some risk of developing type 1 diabetes mellitus." in: Pediatric diabetes, Vol. 10, Issue 6, pp. 382-8, 2009 (PubMed).

Cuesta-Muñoz, Tuomi, Cobo-Vuilleumier et al.: "Clinical heterogeneity in monogenic diabetes caused by mutations in the glucokinase gene (GCK-MODY)." in: Diabetes Care, Vol. 33, Issue 2, pp. 290-2, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Hosts (25), (3)
Reactivities (28), (19), (17), (4), (3)
Applications (28), (13), (5), (2), (1)
Epitopes (5), (3), (2), (2), (1), (1)
back to top