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Asparagine-Linked Glycosylation 8, alpha-1,3-Glucosyltransferase Homolog (S. Cerevisiae) (ALG8) antibody
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||ALG8 (NP_076984, 260 a.a. ~ 335 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: MGC2840 asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase)|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||ALG8 (NP_076984, 260 a.a. ~ 335 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||60088 DA|
Background: This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
|Detection limit for recombinant GST tagged ALG8 is approximately 0.3ng/ml as a capture antibody.|
Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).
Otsuki, Ota, Nishikawa et al.: "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 12, Issue 2, pp. 117-26, 2005 (PubMed).
Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).
Stölting, Omran, Erlekotte et al.: "Novel ALG8 mutations expand the clinical spectrum of congenital disorder of glycosylation type Ih." in: Molecular genetics and metabolism, Vol. 98, Issue 3, pp. 305-9, 2009 (PubMed).
Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).
|Reactivities||Human (3), Rat (Rattus) (3), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1), Mouse (Murine) (1), Pig (Porcine) (1)|
|Applications||Western Blotting (WB) (4), ELISA (1)|
|Epitopes||Internal Region (1), N-Term,AA 14-41 (1)|