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Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-474) antibody

Details for Product No. ABIN393438, Supplier: Login to see
Antigen
  • CAMK4
  • camk4-A
  • CaMK IV
  • CaMK-GR
  • IV
  • caMK
  • A430110E23Rik
  • AI666733
  • CaMKIV
  • CaMKIV/Gr
  • D18Bwg0362e
  • Ccdpk
  • RATCCDPK
  • wu:fj42a03
  • zgc:110275
Alternatives
anti-Human Calcium/calmodulin-Dependent Protein Kinase IV antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 1-474
28
21
20
15
9
6
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
117
88
62
3
3
3
2
2
2
2
1
1
1
Host
Mouse
122
24
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Western Blotting (WB)
114
58
47
39
29
22
13
9
5
3
2
1
1
Supplier
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Immunogen CAMK4 (AAH25687, 1 a.a. ~ 474 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1A3
Isotype IgG1 kappa
Specificity CAMK4 (AAH25687, 1 a.a. ~ 474 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name CAMK4 (CAMK4 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 51926 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Transcription Factors, Cell Structure
Pathways EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Western blot = 1:500-1000
Comment

Background: The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-474) antibody (ABIN393438) Immunofluorescence of monoclonal antibody to CAMK4 used as specificity and loading co...
Immunohistochemistry (IHC) image for anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-474) antibody (ABIN393438) anti-Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) (AA 1-474) antibody (Image 2)
Background publications Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Aston, Krausz, Laface et al.: "Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent." in: Human reproduction (Oxford, England), Vol. 25, Issue 6, pp. 1383-97, 2010 (PubMed).

You, Peng, Lin et al.: "PLC/CAMK IV-NF-kappaB involved in the receptor for advanced glycation end products mediated signaling pathway in human endothelial cells." in: Molecular and cellular endocrinology, Vol. 320, Issue 1-2, pp. 111-7, 2010 (PubMed).

Feliciano, Edelman: "Repression of Ca2+/calmodulin-dependent protein kinase IV signaling accelerates retinoic acid-induced differentiation of human neuroblastoma cells." in: The Journal of biological chemistry, Vol. 284, Issue 39, pp. 26466-81, 2009 (PubMed).