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Details for Product No. ABIN393438

Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4) antibody

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Antigen
Synonyms CaMK IV, CaMK-GR, IV, caMK, CaMKIV, AI666733, CaMKIV/Gr, D18Bwg0362e, A430110E23Rik, Ccdpk, RATCCDPK, camk4-A, wu:fj42a03, zgc:110275, CAMK4
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN393438
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen CAMK4 (AAH25687, 1 a.a. ~ 474 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1A3
Isotype IgG1 kappa
Specificity CAMK4 (AAH25687, 1 a.a. ~ 474 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name CAMK4
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 51926 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Transcription Factors, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml Immunofluorescence
Comment

Background: The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Feliciano, Edelman: "Repression of Ca2+/calmodulin-dependent protein kinase IV signaling accelerates retinoic acid-induced differentiation of human neuroblastoma cells." in: The Journal of biological chemistry, Vol. 284, Issue 39, pp. 26466-81, 2009 (PubMed).

You, Peng, Lin et al.: "PLC/CAMK IV-NF-kappaB involved in the receptor for advanced glycation end products mediated signaling pathway in human endothelial cells." in: Molecular and cellular endocrinology, Vol. 320, Issue 1-2, pp. 111-7, 2010 (PubMed).

Aston, Krausz, Laface et al.: "Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent." in: Human reproduction (Oxford, England), Vol. 25, Issue 6, pp. 1383-97, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Alternatives for antigen "Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4)", type "Antibodies"
Hosts (86), (11)
Reactivities (89), (55), (52), (28), (26), (25), (5), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Applications (72), (35), (29), (22), (20), (15), (10), (7), (4), (3), (2), (1), (1), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (18), (18), (10), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
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