|+1 404 474 4654|
|+1 888 205 9894 (TF)|
F-Box and Leucine-Rich Repeat Protein 3 (FBXL3) antibody
|Synonyms||FBL3, FBL3A, FBXL3A, FBK, Ovtm, Fbl3a, Fbxl3a, AU041772, AW212966, fbxl3, MGC80572, FBXL3, MGC151742, F7A7.240, F7A7_240|
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Quantity||0.1mg (1 mg/ml)|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||FBXL3 (NP_036290, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: FBL3, FBL3A, FBXL3AF-box and leucine-rich repeat protein 3|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||FBXL3 (NP_036290, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||48707 DA|
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Ubiquitin-related antibodies, Phospho-specific antibodies, Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
|FBXL3 monoclonal antibody (M03), clone 1A3. Western Blot analysis of FBXL3 expression in HeLa ( Cat # L013V1 ).|
Ilyin, Rialland, Pigeon et al.: "cDNA cloning and expression analysis of new members of the mammalian F-box protein family." in: Genomics, Vol. 67, Issue 1, pp. 40-7, 2000 (PubMed).
Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).
Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).
Kimura, Wakamatsu, Suzuki et al.: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." in: Genome research, Vol. 16, Issue 1, pp. 55-65, 2006 (PubMed).
Busino, Bassermann, Maiolica et al.: "SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins." in: Science (New York, N.Y.), Vol. 316, Issue 5826, pp. 900-4, 2007 (PubMed).
|Hosts||Rabbit (30), Goat (5), Mouse (2)|
|Reactivities||Human (29), Mouse (Murine) (28), Rat (Rattus) (21), Cow (Bovine) (19), Dog (Canine) (3), Chicken (1), Xenopus laevis (1), Zebrafish (1)|
|Applications||Western Blotting (WB) (21), Immunofluorescence (IF) (15), ELISA (9), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (IHC) (3), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)|
|Epitopes||C-Term (3), Internal Region (1), N-Term (1)|