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Cyclin-Dependent Kinase 13 (CDK13) (AA 1-325) antibody

Details for Product No. ABIN393461
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Antigen
Synonyms CDC2L5, cdc2l5, wu:fe16d10, wu:fi49c05, CDC2L, CHED, hCDK13, 2310015O17Rik, Cdc2l5
Epitope
AA 1-325
(12), (7), (7), (6), (1), (1), (1), (1)
Reactivity
Human
(28), (18), (11), (11), (11), (11)
Host
Mouse
(26), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(24), (21), (9), (7), (6), (2), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
Options
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Catalog No. ABIN393461
450.00 $
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Immunogen CDC2L5 (AAH01274, 1 a.a. ~ 325 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1B3-1B11
Isotype IgG1 kappa
Specificity CDC2L5 (AAH01274, 1 a.a. ~ 325 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name CDC2L5
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 164923 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Cell Cycle, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-325) antibody Immunofluorescence of monoclonal antibody to CDC2L5 on HeLa cell (antibody concentration 10 µg/mL). CDC2L5 monoclonal antibody (M01), clone 1B3-1B11 Western Blot analysis of CDC2L5 expression in Hela NE.
anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-325) antibody (2) anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-325) antibody (Image 2)
Background publications Even, Durieux, Escande et al.: "CDC2L5, a Cdk-like kinase with RS domain, interacts with the ASF/SF2-associated protein p32 and affects splicing in vivo." in: Journal of cellular biochemistry, Vol. 99, Issue 3, pp. 890-904, 2006 (PubMed).

Tsang, Connell, Brown et al.: "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex." in: Genomics, Vol. 88, Issue 3, pp. 333-46, 2006 (PubMed).

Beausoleil, Villén, Gerber et al.: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." in: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, 2006 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Malumbres, Harlow, Hunt et al.: "Cyclin-dependent kinases: a family portrait." in: Nature cell biology, Vol. 11, Issue 11, pp. 1275-6, 2009 (PubMed).

Validation Images
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