Cyclin-Dependent Kinase 13 (CDK13) antibody

Antigen: Cyclin-Dependent Kinase 13 (CDK13)

Synonyms: CDC2L5, cdc2l5, KIAA0904, wu:fe16d10, wu:fi49c05, CHED, CDC2L, FLJ35215, KIAA1791, Cdc2l5, 2310015O17Rik

Clonality: Monoclonal (1B3-1B11)

Host: Mouse

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Immunofluorescence (IF), Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN393461

Additional Information

Alternative name: CDC2L5

Gene ID: 8621

Immunogen: CDC2L5 (AAH01274, 1 a.a. ~ 325 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 1B3-1B11

Description: Other names: CDC2L, CHED, KIAA1791cell division cycle 2-like 5 (cholinesterase-related cell division controller)

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: CDC2L5 (AAH01274, 1 a.a. ~ 325 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 164923 DA

Comments:

Background: The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunofluorescence

Concentration: 1 mg/ml

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Protein Modifications, Cell Cycle, Cell Structure

Restrictions: For Research Use only

Images

Immunofluorescence of monoclonal antibody to CDC2L5 (AT1460a) on HeLa cell. [antibody concentration 10ug/ml] CDC2L5 monoclonal antibody (M01), clone 1B3-1B11 Western Blot analysis of CDC2L5 expression in Hela NE ( Cat # L013V3 ).

anti-Cyclin-Dependent Kinase 13 (CDK13) antibody (Image 2)

Publications

Product: Even, Durieux, Escande et al.: "CDC2L5, a Cdk-like kinase with RS domain, interacts with the ASF/SF2-associated protein p32 and affects splicing in vivo." in: Journal of cellular biochemistry, Vol. 99, Issue 3, pp. 890-904, 2006 (PubMed).

Tsang, Connell, Brown et al.: "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex." in: Genomics, Vol. 88, Issue 3, pp. 333-46, 2006 (PubMed).

Beausoleil, Villén, Gerber et al.: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." in: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, 2006 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Malumbres, Harlow, Hunt et al.: "Cyclin-dependent kinases: a family portrait." in: Nature cell biology, Vol. 11, Issue 11, pp. 1275-6, 2009 (PubMed).