You are viewing an incomplete version of our website. Please click to reload the website as full version.

Oxidative-Stress Responsive 1 (OXSR1) (Met19) antibody

Details for Product No. ABIN393465, Supplier: Login to see
Antigen
  • zgc:55494
  • zgc:77321
  • OXSR1
  • OSR1
  • Osr1
  • 2210022N24Rik
  • 2810422B09Rik
  • AI462649
  • AW209236
  • mKIAA1101
Epitope
Met19
18
16
15
13
12
9
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
90
38
21
2
Host
Mouse
58
41
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
81
59
39
26
18
11
11
5
1
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen OXSR1 (AAH08726, 1 a.a. ~ 528 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1B9
Isotype IgG2a kappa
Specificity OXSR1 (AAH08726, 1 a.a. ~ 528 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name OXSR1 (OXSR1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 58022 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Pathways
Application Notes Western blot = 1:500-1000
Comment

Background: The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Oxidative-Stress Responsive 1 (OXSR1) (Met19) antibody (ABIN393465) Immunofluorescence of monoclonal antibody to OXSR1 on HeLa cell (antibody concentrati...
Immunohistochemistry (IHC) image for anti-Oxidative-Stress Responsive 1 (OXSR1) (Met19) antibody (ABIN393465) anti-Oxidative-Stress Responsive 1 (OXSR1) (Met19) antibody (Image 2)
Background publications Lee, Cobb, Goldsmith: "Crystal structure of domain-swapped STE20 OSR1 kinase domain." in: Protein science : a publication of the Protein Society, Vol. 18, Issue 2, pp. 304-13, 2009 (PubMed).

Villa, Deak, Alessi et al.: "Structure of the OSR1 kinase, a hypertension drug target." in: Proteins, Vol. 73, Issue 4, pp. 1082-7, 2008 (PubMed).

Richardson, Rafiqi, Karlsson et al.: "Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1." in: Journal of cell science, Vol. 121, Issue Pt 5, pp. 675-84, 2008 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Villa, Goebel, Rafiqi et al.: "Structural insights into the recognition of substrates and activators by the OSR1 kinase." in: EMBO reports, Vol. 8, Issue 9, pp. 839-45, 2007 (PubMed).