Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (AA 1-160) antibody

Details for Product No. ABIN393489
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms zgc:77806, GADD45G, XGadd45-gamma, cr6, ddit2, gadd45gamma, grp17, xgadd45g, AI327420, C86281, CR6, DDIT2, OIG37, GADD45gamma, GRP17
Epitope
AA 1-160
(10), (9), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(60), (15), (14), (11), (11), (11)
Host
Mouse
(28), (23), (8), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(44), (19), (10), (9), (7), (2), (2), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
Options
Shipping to United States (Change)
Availability Will be delivered in 8 to 11 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN393489
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen GADD45G (AAH19325, 1 a.a. ~ 160 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1D3
Isotype IgG2a kappa
Specificity GADD45G (AAH19325, 1 a.a. ~ 160 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name GADD45G
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 17121 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (AA 1-160) antibody Detection limit for recombinant GST tagged GADD45G is approximately 0.03 ng/mL as a capture antibody.
Background publications Zhang, Zhao, Li et al.: "Purification, crystallization and preliminary X-ray diffraction analysis of human Gadd45gamma." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 64, Issue Pt 11, pp. 1070-3, 2008 (PubMed).

Zhu, Shao, Xu et al.: "Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells." in: Molecular biology reports, Vol. 36, Issue 8, pp. 2075-85, 2009 (PubMed).

Palmieri, Wilson, Iversen et al.: "Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3567-72, 2008 (PubMed).

Yu, Cho, Park et al.: "Urinary GADD45gamma expression is associated with progression of lgA nephropathy." in: American journal of nephrology, Vol. 30, Issue 2, pp. 135-9, 2009 (PubMed).

Zhang, Li, Shao et al.: "Semi-quantitative detection of GADD45-gamma methylation levels in gastric, colorectal and pancreatic cancers using methylation-sensitive high-resolution melting analysis." in: Journal of cancer research and clinical oncology, Vol. 136, Issue 8, pp. 1267-73, 2010 (PubMed).

Validation Images
Did you look for something else?
back to top