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S100 Calcium Binding Protein A1 (S100A1) antibody
|Synonyms||S100, S100A, S100-alpha, S100a1, S100A1, MGC159706, DKFZp468K0511|
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||S100A1 (NP_006262, 1 a.a. ~ 76 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: S100, S100A S100 calcium binding protein A1|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||S100A1 (NP_006262, 1 a.a. ~ 76 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||10546 DA|
Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Phospho-specific antibodies, Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
Yusenko, Zubakov, Kovacs: "Gene expression profiling of chromophobe renal cell carcinomas and renal oncocytomas by Affymetrix GeneChip using pooled and individual tumours." in: International journal of biological sciences, Vol. 5, Issue 6, pp. 517-27, 2009 (PubMed).
DeRycke, Andersen, Harrington et al.: "S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival." in: American journal of clinical pathology, Vol. 132, Issue 6, pp. 846-56, 2009 (PubMed).
Sviatoha, Tani, Kleina et al.: "Immunohistochemical analysis of the S100A1, S100B, CD44 and Bcl-2 antigens and the rate of cell proliferation assessed by Ki-67 antibody in benign and malignant melanocytic tumours." in: Melanoma research, Vol. 20, Issue 2, pp. 118-25, 2010 (PubMed).
Marlatt, Spratt, Shaw: "Codon optimization for enhanced Escherichia coli expression of human S100A11 and S100A1 proteins." in: Protein expression and purification, Vol. 73, Issue 1, pp. 58-64, 2010 (PubMed).
van Dieck, Lum, Teufel et al.: "S100 proteins interact with the N-terminal domain of MDM2." in: FEBS letters, Vol. 584, Issue 15, pp. 3269-74, 2010 (PubMed).