WD Repeat Domain 6 (WDR6) antibody

Antigen: WD Repeat Domain 6 (WDR6)

Synonyms: FLJ10218, FLJ52552, FLJ56107, MGC126756, MGC142027, mWDR6, MGC105944, WDR6, MGC166101, DKFZp469K1118

Clonality: Monoclonal (2D4)

Host: Mouse

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN393597

Additional Information

Alternative name: WDR6

Gene ID: 11180

Immunogen: WDR6 (AAH02826, 1 a.a. ~ 290 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG2a lambda

Clone: 2D4

Description: Other names: FLJ10218 WD repeat domain 6

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: WDR6 (AAH02826, 1 a.a. ~ 290 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 121725 DA

Comments:

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Publications

Product: Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Xie, Wang, Chen: "Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27(Kip1) induction." in: Molecular and cellular biochemistry, Vol. 301, Issue 1-2, pp. 115-22, 2007 (PubMed).

Chiba, Inoue, Mizuno et al.: "Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity." in: Neurobiology of aging, Vol. 30, Issue 3, pp. 474-82, 2009 (PubMed).