WD Repeat Domain 6 (WDR6) antibody

Details for Product No. ABIN393597
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Antigen
Synonyms mWDR6, WDR6
Reactivity
Human
(7), (4), (4), (1), (1)
Host
Mouse
(6), (2)
Clonality (Clone)
Monoclonal ()
Application
ELISA, Western Blotting (WB)
(8), (4), (3), (3)
Pubmed 5 references available
Catalog no. ABIN393597
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Immunogen WDR6 (AAH02826, 1 a.a. ~ 290 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2D4
Isotype IgG2a lambda
Specificity WDR6 (AAH02826, 1 a.a. ~ 290 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name WDR6
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 121725 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Xie, Wang, Chen: "Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27(Kip1) induction." in: Molecular and cellular biochemistry, Vol. 301, Issue 1-2, pp. 115-22, 2007 (PubMed).

Chiba, Inoue, Mizuno et al.: "Identification and characterization of an insulin receptor substrate 4-interacting protein in rat brain: implications for longevity." in: Neurobiology of aging, Vol. 30, Issue 3, pp. 474-82, 2009 (PubMed).

Hosts (6), (2)
Reactivities (7), (4), (4), (1), (1)
Applications (8), (4), (3), (3)
Epitopes (2), (1), (1)
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