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MAPK13 antibody (Mitogen-Activated Protein Kinase 13) (AA 251-365)

Details for Product anti-MAPK13 Antibody No. ABIN393602, Supplier: Log in to see
Antigen
  • F24B9.3
  • F24B9_3
  • MAPK-13
  • MAPK 13
  • p38delta
  • Prkm13
  • prkm13
  • PRKM13
  • sapk4
  • SAPK4
  • Serk4
Alternatives
anti-Human MAPK13 antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 251-365
24
21
15
10
8
5
5
4
4
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
148
29
25
4
4
2
2
Host
Mouse
87
63
Clonality (Clone)
Monoclonal ()
Conjugate
This MAPK13 antibody is un-conjugated
4
4
4
4
3
3
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
128
59
58
24
19
11
8
5
4
2
1
Supplier
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Immunogen MAPK13 (AAH00433, 251 a.a. ~ 365 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2D8
Isotype IgG2b kappa
Specificity MAPK13 (AAH00433, 251 a.a. ~ 365 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name MAPK13 (MAPK13 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 42090 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Cell Cycle, Transcription Factors, Cell Structure
Pathways MAPK Signaling, Neurotrophin Signaling Pathway
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MAPK13 antibody (Mitogen-Activated Protein Kinase 13) (AA 251-365) (ABIN393602) Immunofluorescence of monoclonal antibody to MAPK13 on MCF-7 cell (antibody concentra...
Immunohistochemistry (IHC) image for anti-MAPK13 antibody (Mitogen-Activated Protein Kinase 13) (AA 251-365) (ABIN393602) anti-Mitogen-Activated Protein Kinase 13 (MAPK13) (AA 251-365) antibody (Image 2)
Background publications Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010

Ozawa, Ito, Kato, Kubota, Hata: "Human p38 delta MAP kinase mediates UV irradiation induced up-regulation of the gene expression of chemokine BRAK/CXCL14." in: Biochemical and biophysical research communications, Vol. 396, Issue 4, pp. 1060-4, 2010

Efimova: "p38delta mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis." in: Cell cycle (Georgetown, Tex.), Vol. 9, Issue 3, pp. 498-05, 2010

Segat, Brandão, Guimarães, Pontillo, Athanasakis, de Oliveira, Arraes, de Lima Filho, Crovella: "Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment." in: Vaccine, Vol. 28, Issue 10, pp. 2201-6, 2010

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009