You are viewing an incomplete version of our website. Please click to reload the website as full version.

Vaccinia Related Kinase 2 (VRK2) (AA 260-360) antibody

Details for Product No. ABIN393663, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms 2810003O05Rik, AI447698
AA 260-360
(17), (15), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1)
(28), (25), (5)
(37), (6), (1)
Clonality (Clone)
Monoclonal ()
(2), (2), (2), (2), (2), (2)
Immunofluorescence (IF), Western Blotting (WB)
(41), (26), (3), (2), (1)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen VRK2 (AAH27854, 260 a.a. ~ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3B10
Isotype IgG1 kappa
Specificity VRK2 (AAH27854, 260 a.a. ~ 360 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name VRK2 (VRK2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 58141 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Cancer, Cell Structure
Application Notes Western blot = 1:500-1000

Background: This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, leukocytes, fetal liver, and carcinomas. Its protein localizes to the endoplasmic reticulum and has been shown to phosphorylate casein and undergo autophosphorylation. Multiple alternatively spliced transcript variants have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Vaccinia Related Kinase 2 (VRK2) (AA 260-360) antibody (ABIN393663) Immunofluorescence of monoclonal antibody to VRK2 on HeLa cell (antibody concentratio...
Immunohistochemistry (IHC) image for anti-Vaccinia Related Kinase 2 (VRK2) (AA 260-360) antibody (ABIN393663) anti-Vaccinia Related Kinase 2 (VRK2) (AA 260-360) antibody (Image 2)
Background publications Stefansson, Ophoff, Steinberg et al.: "Common variants conferring risk of schizophrenia." in: Nature, Vol. 460, Issue 7256, pp. 744-7, 2009 (PubMed).

Sanz-García, López-Sánchez, Lazo: "Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 11, pp. 2199-214, 2008 (PubMed).

Valbuena, Blanco, Vega et al.: "The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53." in: PLoS ONE, Vol. 3, Issue 7, pp. e2649, 2008 (PubMed).

Blanco, Sanz-García, Santos et al.: "Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein." in: PLoS ONE, Vol. 3, Issue 2, pp. e1660, 2008 (PubMed).

Blanco, Santos, Lazo: "Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1." in: Molecular and cellular biology, Vol. 27, Issue 20, pp. 7273-83, 2007 (PubMed).

Catalog No. ABIN393663
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)