|+1 404 474 4654|
|+1 888 205 9894 (TF)|
RAD23 Homolog A (S. Cerevisiae) (RAD23A) antibody
|Synonyms||HHR23A, MGC111083, HR23A, mHR23A, AL024030, 2310040P19Rik, zgc:92001, wu:fe11h06, RAD23A, MGC140027|
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||RAD23A (AAH14026, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: HHR23A, MGC111083 RAD23 homolog A (S. cerevisiae)|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||RAD23A (AAH14026, 151 a.a. ~ 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||39609 DA|
Background: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Ubiquitin-related antibodies, Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).
Monsees, Kraft, Chanock et al.: "Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk." in: Breast cancer research and treatment, Vol. 125, Issue 1, pp. 207-14, 2010 (PubMed).
Briggs, Goldstein, McCauley et al.: "Variation within DNA repair pathway genes and risk of multiple sclerosis." in: American journal of epidemiology, Vol. 172, Issue 2, pp. 217-24, 2010 (PubMed).
Li, Elder, Dubrovsky et al.: "HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome." in: PLoS ONE, Vol. 5, Issue 6, pp. e11371, 2010 (PubMed).
Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).
|Hosts||Rabbit (26), Goat (5)|
|Reactivities||Human (27), Mouse (Murine) (9), Rat (Rattus) (6), Dog (Canine) (4), Cow (Bovine) (3), Rabbit (2)|
|Applications||Western Blotting (WB) (29), ELISA (23), Immunohistochemistry (IHC) (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunofluorescence (IF) (3), Immunoprecipitation (IP) (1)|
|Conjugates||Biotin (1), FITC (1), HRP (1)|
|Epitopes||N-Term (5), C-Term (3), AA 122-135 (2), Internal Region (2)|