Ubiquitin-Conjugating Enzyme E2H (UBE2H) antibody

Details for Product No. ABIN393686
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Antigen
Synonyms E2-20K, GID3, UBC8, UBCH, UBCH2, 1500009C23Rik, AI181839, AI326965, AI462483, AW227540, Gid3, N28148, Ubc8, fc07a05, fi24c01, wu:fc07a05, wu:fi24c01, si:bz3c13.2, e2-20k, ubc8, ubch, ubch2
Reactivity
Human
(16), (16), (12), (12), (12), (12)
Host
Mouse
(21), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(14), (10), (9), (3), (3)
Pubmed 5 references available
Catalog no. ABIN393686
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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  • +1 404 474 4654
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Immunogen UBE2H (AAH06277, 1 a.a. ~ 184 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3C4-1A2
Isotype IgG2a kappa
Specificity UBE2H (AAH06277, 1 a.a. ~ 184 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name UBE2H
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 20655 DA
Gene ID 12406
Research Area Ubiquitin-related antibodies, Protein Modifications, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Ubiquitin-Conjugating Enzyme E2H (UBE2H) antibody Immunofluorescence of monoclonal antibody to UBE2H on HeLa cell (antibody concentration 10 µg/mL). UBE2H monoclonal antibody (M01), clone 3C4-1A2 Western Blot analysis of UBE2H expression in HeLa.
anti-Ubiquitin-Conjugating Enzyme E2H (UBE2H) antibody (2) anti-Ubiquitin-Conjugating Enzyme E2H (UBE2H) antibody (Image 2)
Background publications Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

in: (PubMed).

de Krom, Staal, Ophoff et al.: "A common variant in DRD3 receptor is associated with autism spectrum disorder." in: Biological psychiatry, Vol. 65, Issue 7, pp. 625-30, 2009 (PubMed).

Martin, Vourch, Mahé et al.: "Association study of the ubiquitin conjugating enzyme gene UBE2H in sporadic ALS." in: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, Vol. 10, Issue 5-6, pp. 432-5, 2009 (PubMed).

Lausen, Pless, Leonard et al.: "Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5338-46, 2010 (PubMed).

Hosts (21), (3)
Reactivities (16), (16), (12), (12), (12), (12)
Applications (14), (10), (9), (3), (3)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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