You are viewing an incomplete version of our website. Please click to reload the website as full version.

Interleukin 23 Receptor (IL23R) (AA 553-629) antibody

Details for Product No. ABIN393707, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms IL-23R, IL23R, il-23r
AA 553-629
(17), (15), (13), (5), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
(62), (27), (23)
(49), (10), (5), (5)
Clonality (Clone)
Monoclonal ()
(4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(48), (25), (14), (11), (8), (7), (4), (2), (1), (1), (1)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen IL23R (NP_653302, 553 a.a. ~ 629 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D7
Isotype IgG2a kappa
Specificity IL23R (NP_653302, 553 a.a. ~ 629 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name IL23R (IL23R Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 71706 DA
Gene ID 12406
NCBI Accession NP_653302
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Transcription Factors, Cell Structure
Application Notes Western blot = 1:500-1000

Background: The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Interleukin 23 Receptor (IL23R) (AA 553-629) antibody (ABIN393707) IL23R monoclonal antibody (M01), clone 3D7 Western Blot analysis of IL23R expression ...
Immunohistochemistry (IHC) image for anti-Interleukin 23 Receptor (IL23R) (AA 553-629) antibody (ABIN393707) anti-Interleukin 23 Receptor (IL23R) (AA 553-629) antibody (Image 2)
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Elmaagacli, Steckel, Ditschkowski et al.: "Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donors." in: Bone marrow transplantation, Vol. 46, Issue 5, pp. 702-8, 2011 (PubMed).

Mizuki, Meguro, Ota et al.: "Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci." in: Nature genetics, Vol. 42, Issue 8, pp. 703-6, 2010 (PubMed).

Remmers, Cosan, Kirino et al.: "Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease." in: Nature genetics, Vol. 42, Issue 8, pp. 698-702, 2010 (PubMed).

Chen, Lu, Zhang et al.: "A nonsynonymous polymorphism in IL23R gene is associated with risk of gastric cancer in a Chinese population." in: Molecular carcinogenesis, Vol. 49, Issue 10, pp. 862-8, 2010 (PubMed).

Catalog No. ABIN393707
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)