Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) (AA 431-531) antibody

Details for Product No. ABIN393724
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Synonyms DUB-3, Dub3, Dub6, EG625530, Gm6596, USP17, Usp17l2, DUB3
AA 431-531
(17), (16), (2), (2), (2), (2), (1), (1), (1)
(23), (4)
Clonality (Clone)
Monoclonal ()
(2), (2), (2), (2), (2), (2)
ELISA, Western Blotting (WB)
(26), (15), (3), (1), (1)
Pubmed 4 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen DUB3 (NP_958804, 431 a.a. ~ 531 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G12
Isotype IgG1 kappa
Specificity DUB3 (NP_958804, 431 a.a. ~ 531 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DUB3 (USP17L2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 59711 DA
Gene ID 12406
NCBI Accession NP_958804
Research Area Ubiquitin-related antibodies, Protein Modifications, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Background: DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for Background: information.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) (AA 431-531) antibody (ABIN393724) Detection limit for recombinant GST tagged DUB3 is approximately 0.3 ng/mL as a captu...
Background publications Pereg, Liu, ORourke et al.: "Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A." in: Nature cell biology, Vol. 12, Issue 4, pp. 400-6, 2010 (PubMed).

Alkan, Kidd, Marques-Bonet et al.: "Personalized copy number and segmental duplication maps using next-generation sequencing." in: Nature genetics, Vol. 41, Issue 10, pp. 1061-7, 2009 (PubMed).

Sowa, Bennett, Gygi et al.: "Defining the human deubiquitinating enzyme interaction landscape." in: Cell, Vol. 138, Issue 2, pp. 389-403, 2009 (PubMed).

Burrows, McGrattan, Rascle et al.: "DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation." in: The Journal of biological chemistry, Vol. 279, Issue 14, pp. 13993-4000, 2004 (PubMed).

Catalog No. ABIN393724
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