Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) (AA 431-531) antibody

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Antigen
Synonyms DUB-3, Dub3, Dub6, EG625530, Gm6596, USP17, Usp17l2, DUB3
Epitope
AA 431-531
(18), (16), (2), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(29)
Host
Mouse
(24), (5)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
ELISA, Western Blotting (WB)
(28), (16), (3), (1), (1), (1)
Pubmed 4 references available
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Quantity 0.1 mg
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Immunogen DUB3 (NP_958804, 431 a.a. ~ 531 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G12
Isotype IgG1 kappa
Specificity DUB3 (NP_958804, 431 a.a. ~ 531 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DUB3 (USP17L2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 59711 DA
Gene ID 12406
NCBI Accession NP_958804
Research Area Ubiquitin-related antibodies, Protein Modifications, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for Background: information.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) (AA 431-531) antibody (ABIN393724) Detection limit for recombinant GST tagged DUB3 is approximately 0.3 ng/mL as a captu...
Background publications Pereg, Liu, ORourke et al.: "Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A." in: Nature cell biology, Vol. 12, Issue 4, pp. 400-6, 2010 (PubMed).

Alkan, Kidd, Marques-Bonet et al.: "Personalized copy number and segmental duplication maps using next-generation sequencing." in: Nature genetics, Vol. 41, Issue 10, pp. 1061-7, 2009 (PubMed).

Sowa, Bennett, Gygi et al.: "Defining the human deubiquitinating enzyme interaction landscape." in: Cell, Vol. 138, Issue 2, pp. 389-403, 2009 (PubMed).

Burrows, McGrattan, Rascle et al.: "DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation." in: The Journal of biological chemistry, Vol. 279, Issue 14, pp. 13993-4000, 2004 (PubMed).

Catalog No. ABIN393724
$450.00
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