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Details for Product No. ABIN393724

Ubiquitin Specific Peptidase 17-Like 2 (USP17L2) antibody

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Antigen
Synonyms DUB-3, DUB3, USP17, Dub3, Dub6, EG625530, Gm6596, Usp17l2
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN393724
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen DUB3 (NP_958804, 431 a.a. ~ 531 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3G12
Isotype IgG1 kappa
Specificity DUB3 (NP_958804, 431 a.a. ~ 531 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DUB3
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 59711 DA
Gene ID 12406
UniProt NP_958804
Research Area Ubiquitin-related antibodies, Protein Modifications, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: DUB3 is a member of the ubiquitin processing protease (UBP) subfamily of deubiquitinating enzymes. See USP1 (MIM 603478) for Background: information.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Burrows, McGrattan, Rascle et al.: "DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation." in: The Journal of biological chemistry, Vol. 279, Issue 14, pp. 13993-4000, 2004 (PubMed).

Sowa, Bennett, Gygi et al.: "Defining the human deubiquitinating enzyme interaction landscape." in: Cell, Vol. 138, Issue 2, pp. 389-403, 2009 (PubMed).

Alkan, Kidd, Marques-Bonet et al.: "Personalized copy number and segmental duplication maps using next-generation sequencing." in: Nature genetics, Vol. 41, Issue 10, pp. 1061-7, 2009 (PubMed).

Pereg, Liu, ORourke et al.: "Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A." in: Nature cell biology, Vol. 12, Issue 4, pp. 400-6, 2010 (PubMed).

Alternatives for antigen "Ubiquitin Specific Peptidase 17-Like 2 (USP17L2)", type "Antibodies"
Hosts (8), (2)
Reactivities (10)
Applications (10), (3), (1)
Epitopes (5), (2), (2), (2), (1), (1), (1)
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