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Details for Product No. ABIN393788

ASF1 Anti-Silencing Function 1 Homolog B (S. Cerevisiae) (ASF1B) antibody

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Antigen
Synonyms CIA-II, AA409591, 1700003K02Rik, asf1b, fc68a10, wu:fc68a10, zgc:77178, F16F17.110, F16F17_110, SGA01, SGA1, anti- silencing function 1b, ASF1B, asf1, MGC89345
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN393788
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen ASF1B (AAH07726, 1 a.a. ~ 203 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4D5-2C2
Isotype IgG1 kappa
Specificity ASF1B (AAH07726, 1 a.a. ~ 203 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ASF1B
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22434 DA
Gene ID 12406
Research Area Phospho-specific antibodies, Protein Modifications, Chromatin, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Pilyugin, Demmers, Verrijzer et al.: "Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases." in: PLoS ONE, Vol. 4, Issue 12, pp. e8328, 2009 (PubMed).

Peng, Nogueira, Vogel et al.: "Transcriptional coactivator HCF-1 couples the histone chaperone Asf1b to HSV-1 DNA replication components." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 6, pp. 2461-6, 2010 (PubMed).

Jasencakova, Scharf, Ask et al.: "Replication stress interferes with histone recycling and predeposition marking of new histones." in: Molecular cell, Vol. 37, Issue 5, pp. 736-43, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Alternatives for antigen "ASF1 Anti-Silencing Function 1 Homolog B (S. Cerevisiae) (ASF1B)", type "Antibodies"
Hosts (11), (2)
Reactivities (12), (7), (7), (1), (1), (1), (1), (1), (1), (1)
Applications (13), (10), (2), (1)
Epitopes (2), (2), (1), (1)
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