Did you know that you can buy products from over 140 different suppliers from us?

Synapsin I (SYN1) antibody

Details for Product No. ABIN393800
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms SYNI, SYN1a, SYN1b, Syn-1, si:dkey-90n12.3, SYN I, Synapsin-1
Reactivity
Human
(203), (181), (164), (60), (54), (40), (7), (6), (2), (2), (2), (1)
Host
Mouse
(227), (18), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (1), (1), (1)
Application
Western Blotting (WB)
(180), (80), (60), (34), (31), (29), (13), (12), (10), (3), (1), (1)
Pubmed 5 references available
Catalog no. ABIN393800
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen SYN1 (NP_008881, 362 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4F6
Isotype IgG2a kappa
Specificity SYN1 (NP_008881, 362 a.a. ~ 451 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name SYN1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 74111 DA
Gene ID 12406
UniProt NP_008881
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Synapsin I (SYN1) antibody SYN1 monoclonal antibody (M06), clone 4F6 Western Blot analysis of SYN1 expression in MCF-7.
anti-Synapsin I (SYN1) antibody (2) anti-Synapsin I (SYN1) antibody (Image 2)
Background publications Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Gratacòs, Costas, de Cid et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, 2009 (PubMed).

Wang, Chang, Tong et al.: "Human synapsin I mediates the function of nuclear respiratory factor 1 in neurite outgrowth in neuroblastoma IMR-32 cells." in: Journal of neuroscience research, Vol. 87, Issue 10, pp. 2255-63, 2009 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Hosts (227), (18), (1)
Reactivities (203), (181), (164), (60), (54), (40), (7), (6), (2), (2), (2), (1)
Applications (180), (80), (60), (34), (31), (29), (13), (12), (10), (3), (1), (1)
Conjugates (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (1), (1), (1)
Epitopes (45), (27), (26), (22), (21), (16), (7), (6), (6), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top