Histone Deacetylase 5 (HDAC5) (AA 330-429) antibody

Details for Product No. ABIN393805
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms HDAC5, DKFZp459O115, HD5, NY-CO-9, AI426555, Hdac4, mHDA1, mKIAA0600, ATHDA5, HDA5, MAF19.7, MAF19_7, histone deacetylase 5, Hd6, Hdac5, Sfc6, mHDA2
AA 330-429
(31), (21), (12), (7), (5), (4), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(162), (74), (37), (3), (3), (1)
(155), (7)
Clonality (Clone)
Monoclonal ()
(2), (2), (2), (2), (2), (2)
Immunofluorescence (IF), Western Blotting (WB)
(137), (100), (72), (24), (21), (18), (5), (3), (3), (2), (2), (1)
Pubmed 5 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen HDAC5 (AAH51824, 330 a.a. ~ 429 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 4G2
Isotype IgG1 kappa
Specificity HDAC5 (AAH51824, 330 a.a. ~ 429 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name HDAC5 (HDAC5 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 121992 DA
Gene ID 12406
Research Area Signaling, Protein Modifications, Cancer, Transcription Factors, Chromatin, Cell Structure
Application Notes Western blot = 1:500-1000

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Histone Deacetylase 5 (HDAC5) (AA 330-429) antibody (ABIN393805) Immunofluorescence of monoclonal antibody to HDAC5 on HeLa cell (antibody concentrati...
Immunohistochemistry (IHC) image for anti-Histone Deacetylase 5 (HDAC5) (AA 330-429) antibody (ABIN393805) anti-Histone Deacetylase 5 (HDAC5) (AA 330-429) antibody (Image 2)
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Harrison, Huynh, Lundgaard et al.: "Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases." in: FEBS letters, Vol. 584, Issue 6, pp. 1103-10, 2010 (PubMed).

Wang, Ha, Jhun et al.: "Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS." in: Blood, Vol. 115, Issue 14, pp. 2971-9, 2010 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Rivadeneira, Styrkársdottir, Estrada et al.: "Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies." in: Nature genetics, Vol. 41, Issue 11, pp. 1199-206, 2009 (PubMed).

Catalog No. ABIN393805
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?