Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (AA 761-860) antibody

Details for Product No. ABIN393876
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Antigen
Synonyms CNKSR3, AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, TNRC19, WWP3, Baiap1, Gukmi1, MAGI1c, Magi-1, mKIAA4129
Epitope
AA 761-860
(8), (6), (3), (1), (1), (1), (1)
Reactivity
Human
(30), (4), (4)
Host
Mouse
(15), (15)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (2), (2), (2), (2), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(29), (20), (6), (6), (3), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN393876
450.00 $
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Immunogen MAGI1 (NP_004733, 761 a.a. ~ 860 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 7B4
Isotype IgG1 kappa
Specificity MAGI1 (NP_004733, 761 a.a. ~ 860 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name MAGI1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 164641 DA
Gene ID 12406
NCBI Accession NP_004733
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (AA 761-860) antibody Immunofluorescence of monoclonal antibody to MAGI1 on HeLa cell (antibody concentration 10 µg/mL). MAGI1 monoclonal antibody (M03), clone 7B4 Western Blot analysis of MAGI1 expression in PC-12.
anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (AA 761-860) antibody (2) anti-Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) (AA 761-860) antibody (Image 2)
Background publications Zeggini, Scott, Saxena et al.: "Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes." in: Nature genetics, Vol. 40, Issue 5, pp. 638-45, 2008 (PubMed).

Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Ohnishi, Tochio, Tomizawa et al.: "Structural basis for controlling the dimerization and stability of the WW domains of an atypical subfamily." in: Protein science : a publication of the Protein Society, Vol. 17, Issue 9, pp. 1531-41, 2008 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Kaufman, Potla, Coleman et al.: "Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis." in: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25677-85, 2010 (PubMed).

Validation Images
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