|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) antibody
|Synonyms||AIP3, BAP1, WWP3, BAIAP1, MAGI-1, TNRC19, CNKSR3, MAGI1|
Alternatives ELISA, Immunofluorescence (IF), Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||MAGI1 (NP_004733, 761 a.a. ~ 860 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: AIP3, BAIAP1, BAP1, MAGI1, TNRC19, WWP3 membrane associated guanylate kinase, WW and PDZ domain containing 1|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||MAGI1 (NP_004733, 761 a.a. ~ 860 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||164641 DA|
Background: The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunofluorescence|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Phospho-specific antibodies, Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
Zeggini, Scott, Saxena et al.: "Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes." in: Nature genetics, Vol. 40, Issue 5, pp. 638-45, 2008 (PubMed).
Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).
Ohnishi, Tochio, Tomizawa et al.: "Structural basis for controlling the dimerization and stability of the WW domains of an atypical subfamily." in: Protein science : a publication of the Protein Society, Vol. 17, Issue 9, pp. 1531-41, 2008 (PubMed).
Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).
Kaufman, Potla, Coleman et al.: "Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis." in: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25677-85, 2010 (PubMed).
|Reactivities||Human (10), Mouse (Murine) (2), Rat (Rattus) (2), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)|
|Applications||ELISA (8), Western Blotting (WB) (6), Dot Blot (DB) (2), Immunohistochemistry (IHC) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunofluorescence (IF) (1), Immunoprecipitation (IP) (1)|
|Epitopes||C-Term (2), AA 1242-1256 (1)|