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Details for Product No. ABIN393876

Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1) antibody

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Antigen
Synonyms AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, TNRC19, WWP3, Baiap1, Gukmi1, MAGI1c, Magi-1, mKIAA4129, CNKSR3
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Immunofluorescence (IF), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN393876
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen MAGI1 (NP_004733, 761 a.a. ~ 860 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 7B4
Isotype IgG1 kappa
Specificity MAGI1 (NP_004733, 761 a.a. ~ 860 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name MAGI1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 164641 DA
Gene ID 12406
UniProt NP_004733
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunofluorescence
Comment

Background: The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Zeggini, Scott, Saxena et al.: "Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes." in: Nature genetics, Vol. 40, Issue 5, pp. 638-45, 2008 (PubMed).

Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Ohnishi, Tochio, Tomizawa et al.: "Structural basis for controlling the dimerization and stability of the WW domains of an atypical subfamily." in: Protein science : a publication of the Protein Society, Vol. 17, Issue 9, pp. 1531-41, 2008 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Kaufman, Potla, Coleman et al.: "Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis." in: The Journal of biological chemistry, Vol. 285, Issue 33, pp. 25677-85, 2010 (PubMed).

Alternatives for antigen "Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 1 (MAGI1)", type "Antibodies"
Hosts (11), (8)
Reactivities (19), (4), (4)
Applications (17), (8), (3), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1)
Epitopes (4), (3), (2), (1)
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