Remodeling and Spacing Factor 1 (RSF1) (AA 1343-1442) antibody

Details for Product No. ABIN393926
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Antigen
Synonyms Rsf-1, CG5655, Dmel\\CG5655, ROX21, RSF1, Rox21, rox21, hbxap, HBXAP, RSF-1, XAP8, p325, 4832420A03Rik, C030033M12Rik, Gm164, Hbxap
Epitope
AA 1343-1442
(3), (2), (1), (1)
Reactivity
Human
(10), (2), (1), (1), (1), (1), (1)
Host
Mouse
(4), (4), (3)
Clonality (Clone)
Monoclonal ()
Application
ELISA, Western Blotting (WB)
(8), (4), (3), (3), (2), (2)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN393926
450.00 $
Plus shipping costs $45.00

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Immunogen HBXAP (NP_057662, 1343 a.a. ~ 1442 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3E6
Isotype IgG2a kappa
Specificity HBXAP (NP_057662, 1343 a.a. ~ 1442 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name HBXAP
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 163006 DA
Gene ID 12406
NCBI Accession NP_057662
Research Area Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: HBXAP is involved in transcription repression, transcription coactivation when associated with hepatitis B virus X protein (HBX), and chromatin remodeling and spacing when associated with SNF2H (MIM 603375).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Remodeling and Spacing Factor 1 (RSF1) (AA 1343-1442) antibody Detection limit for recombinant GST tagged HBXAP is approximately 0.1 ng/mL as a capture antibody.
Background publications Brown, Kalloger, Miller et al.: "Amplification of 11q13 in ovarian carcinoma." in: Genes, chromosomes & cancer, Vol. 47, Issue 6, pp. 481-9, 2008 (PubMed).

Sheu, Choi, Yildiz et al.: "The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1." in: Cancer research, Vol. 68, Issue 11, pp. 4050-7, 2008 (PubMed).

Choi, Sheu, Guan et al.: "Functional analysis of 11q13.5 amplicon identifies Rsf-1 (HBXAP) as a gene involved in paclitaxel resistance in ovarian cancer." in: Cancer research, Vol. 69, Issue 4, pp. 1407-15, 2009 (PubMed).

Longato, de la Monte, Kuzushita et al.: "Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver." in: Hepatology (Baltimore, Md.), Vol. 49, Issue 6, pp. 1935-43, 2009 (PubMed).

Sehdev, Kurman, Kuhn et al.: "Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 23, Issue 6, pp. 844-55, 2010 (PubMed).

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