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Details for Product No. ABIN393926

Remodeling and Spacing Factor 1 (RSF1) antibody

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Antigen
Synonyms XAP8, p325, HBXAP, RSF-1, Hbxap, Rsf-1, CG5655, Dmel\\CG5655, ROX21, RSF1, Rox21, rox21, 4832420A03Rik, C030033M12Rik, Gm164, hbxap
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN393926
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen HBXAP (NP_057662, 1343 a.a. ~ 1442 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3E6
Isotype IgG2a kappa
Specificity HBXAP (NP_057662, 1343 a.a. ~ 1442 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name HBXAP
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 163006 DA
Gene ID 12406
UniProt NP_057662
Research Area Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: HBXAP is involved in transcription repression, transcription coactivation when associated with hepatitis B virus X protein (HBX), and chromatin remodeling and spacing when associated with SNF2H (MIM 603375).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Brown, Kalloger, Miller et al.: "Amplification of 11q13 in ovarian carcinoma." in: Genes, chromosomes & cancer, Vol. 47, Issue 6, pp. 481-9, 2008 (PubMed).

Sheu, Choi, Yildiz et al.: "The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1." in: Cancer research, Vol. 68, Issue 11, pp. 4050-7, 2008 (PubMed).

Choi, Sheu, Guan et al.: "Functional analysis of 11q13.5 amplicon identifies Rsf-1 (HBXAP) as a gene involved in paclitaxel resistance in ovarian cancer." in: Cancer research, Vol. 69, Issue 4, pp. 1407-15, 2009 (PubMed).

Longato, de la Monte, Kuzushita et al.: "Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver." in: Hepatology (Baltimore, Md.), Vol. 49, Issue 6, pp. 1935-43, 2009 (PubMed).

Sehdev, Kurman, Kuhn et al.: "Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 23, Issue 6, pp. 844-55, 2010 (PubMed).

Alternatives for antigen "Remodeling and Spacing Factor 1 (RSF1)", type "Antibodies"
Hosts (4), (3), (3)
Reactivities (8), (2), (1), (1), (1), (1)
Applications (7), (3), (3), (3), (2), (1)
Epitopes (3), (1), (1), (1)
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