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Upstream Transcription Factor 2, C-Fos Interacting (USF2) (AA 1-101) antibody

Details for Product No. ABIN393956, Supplier: Log in to see
Antigen
  • fip
  • MGC79773
  • bhlhb12
  • USF2
  • Usf-2
  • bHLHb12
  • FIP
  • fb12g11
  • si:dkey-211g8.3
  • wu:fb12g11
  • usf2
Epitope
AA 1-101
20
11
7
5
5
4
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
82
27
17
4
2
1
1
1
1
Host
Mouse
62
26
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunofluorescence (IF), Western Blotting (WB)
74
37
18
16
12
6
6
3
1
1
Supplier
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Immunogen USF2 (NP_003358, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 5E9
Isotype IgG2a kappa
Specificity USF2 (NP_003358, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name USF2 (USF2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 36955 DA
Gene ID 12406
NCBI Accession NP_003358
Research Area Transcription Factors, Signaling, Cell Structure
Pathways
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Upstream Transcription Factor 2, C-Fos Interacting (USF2) (AA 1-101) antibody (ABIN393956) Immunofluorescence of monoclonal antibody to USF2 on HeLa cell (antibody concentratio...
Immunohistochemistry (IHC) image for anti-Upstream Transcription Factor 2, C-Fos Interacting (USF2) (AA 1-101) antibody (ABIN393956) anti-Upstream Transcription Factor 2, C-Fos Interacting (USF2) (AA 1-101) antibody (Image 2)
Background publications Sun, Yu, Degraff et al.: "Upstream stimulatory factor 2, a novel FoxA1-interacting protein, is involved in prostate-specific gene expression." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 12, pp. 2038-47, 2009 (PubMed).

Landa, Ruiz-Llorente, Montero-Conde et al.: "The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors." in: PLoS genetics, Vol. 5, Issue 9, pp. e1000637, 2009 (PubMed).

Wang, Li, Zhang et al.: "HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 7, pp. 1526-34, 2009 (PubMed).

Finotti, Treves, Zorzato et al.: "Upstream stimulatory factors are involved in the P1 promoter directed transcription of the A beta H-J-J locus." in: BMC molecular biology, Vol. 9, pp. 110, 2009 (PubMed).

Agirre, Jiménez-Velasco, San José-Enériz et al.: "Down-regulation of hsa-miR-10a in chronic myeloid leukemia CD34+ cells increases USF2-mediated cell growth." in: Molecular cancer research : MCR, Vol. 6, Issue 12, pp. 1830-40, 2008 (PubMed).