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RAN Binding Protein 3 (RANBP3) (AA 298-397) antibody

Details for Product No. ABIN393959, Supplier: Log in to see
Antigen
  • ranbp3
  • MGC79798
  • 2610024N24Rik
  • AA408221
  • RAN binding protein 3
  • ran binding protein 3
  • RAN binding protein 3-like
  • RANBP3
  • ranbp3
  • Ranbp3
  • RANBP3L
Epitope
AA 298-397
19
15
14
9
8
3
2
1
1
1
1
1
1
Reactivity
Human
75
21
17
2
2
1
1
1
Host
Mouse
53
22
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
4
4
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
56
39
14
10
9
6
4
4
1
1
1
1
Options
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Immunogen RANBP3 (AAH04349, 298 a.a. ~ 397 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2E10
Isotype IgG2a kappa
Specificity RANBP3 (AAH04349, 298 a.a. ~ 397 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name RANBP3 (RANBP3 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 60210 DA
Gene ID 12406
Research Area Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-RAN Binding Protein 3 (RANBP3) (AA 298-397) antibody (ABIN393959) Detection limit for recombinant GST tagged RANBP3 is approximately 0.03 ng/mL as a ca...
Background publications Dai, Lin, Chang, Feng: "Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling." in: Developmental cell, Vol. 16, Issue 3, pp. 345-57, 2009 (PubMed).

Yoon, Shin, Liu, Ballif, Woo, Gygi, Blenis: "Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport." in: Molecular cell, Vol. 29, Issue 3, pp. 362-75, 2008 (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, 2005 (PubMed).