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ZFP36 Ring Finger Protein-Like 1 (ZFP36L1) antibody
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||ZFP36L1 (NP_004917, 1 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: BRF1, Berg36, ERF1, ERF1, RNF162B, TIS11B, cMG1 zinc finger protein 36, C3H type-like 1|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||ZFP36L1 (NP_004917, 1 a.a. ~ 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||36314 DA|
Background: This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Transcription Factors, Signaling, Cell Structure|
|Restrictions||For Research Use only|
Baou, Jewell, Muthurania et al.: "Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 23, Issue 5, pp. 986-9, 2009 (PubMed).
Cheng, Saito, Pisarev et al.: "Structural insights into eRF3 and stop codon recognition by eRF1." in: Genes & development, Vol. 23, Issue 9, pp. 1106-18, 2009 (PubMed).
Sinha, Dutta, Datta et al.: "Von Hippel-Lindau gene product modulates TIS11B expression in renal cell carcinoma: impact on vascular endothelial growth factor expression in hypoxia." in: The Journal of biological chemistry, Vol. 284, Issue 47, pp. 32610-8, 2009 (PubMed).
Hacker, Valchanova, Adams et al.: "ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production." in: Growth factors (Chur, Switzerland), Vol. 28, Issue 3, pp. 178-90, 2010 (PubMed).
Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).
|Hosts||Rabbit (21), Mouse (3)|
|Reactivities||Human (22), Mouse (Murine) (10), Rat (Rattus) (8), Dog (Canine) (4), Cow (Bovine) (3), Fruit Fly (Drosophila melanogaster) (1), Pig (Porcine) (1), Xenopus laevis (1)|
|Applications||Western Blotting (WB) (22), Immunohistochemistry (IHC) (5), ELISA (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Dot Blot (DB) (1), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)|
|Epitopes||N-Term (5), C-Term (2), Internal Region (1)|