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Nuclear Transcription Factor Y, gamma (NFYC) (AA 14-113) antibody

Details for Product No. ABIN394039, Supplier: Login to see
Antigen
  • cbf-c
  • cbfc
  • h1tf2a
  • hap5
  • hsm
  • nf-yc
  • NFYC
  • Nfyc
  • CBF-C
  • CBFC
  • H1TF2A
  • HAP5
  • HSM
  • NF-YC
  • fb98f01
  • wu:fb98f01
  • zgc:55514
Epitope
AA 14-113
24
16
6
3
2
2
2
1
1
1
1
1
1
Reactivity
Human
55
17
16
6
4
3
2
1
1
1
1
1
1
Host
Mouse
52
4
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
48
29
9
5
5
2
2
1
1
1
Supplier
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Immunogen NFYC (AAH05003, 14 a.a. ~ 113 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1D3
Isotype IgG3 kappa
Specificity NFYC (AAH05003, 14 a.a. ~ 113 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name NFYC (NFYC Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 50302 DA
Gene ID 12406
Research Area Transcription Factors, Signaling, Chromatin, Cell Structure
Pathways
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Nuclear Transcription Factor Y, gamma (NFYC) (AA 14-113) antibody (ABIN394039) Western blot analysis of NFYC over-expressed 293 cell line, cotransfected with NFYC V...
Immunohistochemistry (IHC) image for anti-Nuclear Transcription Factor Y, gamma (NFYC) (AA 14-113) antibody (ABIN394039) anti-Nuclear Transcription Factor Y, gamma (NFYC) (AA 14-113) antibody (Image 2)
Background publications Ichikawa, Koller, Padgett et al.: "Replication of previous genome-wide association studies of bone mineral density in premenopausal American women." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 25, Issue 8, pp. 1821-9, 2010 (PubMed).

Murai-Takeda, Shibata, Kurihara et al.: "NF-YC functions as a corepressor of agonist-bound mineralocorticoid receptor." in: The Journal of biological chemistry, Vol. 285, Issue 11, pp. 8084-93, 2010 (PubMed).

Ceribelli, Benatti, Imbriano et al.: "NF-YC complexity is generated by dual promoters and alternative splicing." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 34189-200, 2009 (PubMed).

Yamanaka, Mizuarai, Eguchi et al.: "Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple cancers." in: Genomics, Vol. 94, Issue 4, pp. 219-27, 2009 (PubMed).

Horikawa, Wood, Yang et al.: "Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 23, pp. 7956-62, 2008 (PubMed).