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Density Regulated Protein antibody (Density-Regulated Protein) (AA 1-82)

Details for Product anti-DENR Antibody No. ABIN394092, Supplier: Log in to see
Antigen
  • 1500003K04Rik
  • DDBDRAFT_0205981
  • DDBDRAFT_0266779
  • DDB_0205981
  • DDB_0266779
  • DENR
  • Denr
  • denr
  • DRP
  • drp
  • drp1
  • DRP1
  • im:6891640
  • MGC79758
  • MGC107862
  • SMAP-3
  • smap-3
  • zgc:92629
  • zgc:113309
Epitope
AA 1-82
9
4
4
3
3
3
3
2
2
2
1
1
1
Reactivity
Human
49
13
11
1
1
1
1
1
Host
Mouse
34
14
1
Clonality (Clone)
Monoclonal ()
Conjugate
This Density Regulated Protein antibody is un-conjugated
3
3
3
1
1
1
Application
Western Blotting (WB)
39
23
5
4
3
1
1
1
Supplier
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Immunogen DENR (NP_003668, 1 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1H3
Isotype IgG2a kappa
Specificity DENR (NP_003668, 1 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DENR (DENR Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22092 DA
Gene ID 12406
NCBI Accession NP_003668
Research Area Translation Factors, Signaling, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Density Regulated Protein antibody (Density-Regulated Protein) (AA 1-82) (ABIN394092) Western Blot analysis of DENR expression in transfected 293T cell line by DENR monocl...
Immunohistochemistry (IHC) image for anti-Density Regulated Protein antibody (Density-Regulated Protein) (AA 1-82) (ABIN394092) anti-Density-Regulated Protein (DENR) (AA 1-82) antibody (Image 2)
Background publications Mazan-Mamczarz, Gartenhaus: "Post-transcriptional control of the MCT-1-associated protein DENR/DRP by RNA-binding protein AUF1." in: Cancer genomics & proteomics, Vol. 4, Issue 3, pp. 233-9, 2007 (PubMed).

Yonashiro, Ishido, Kyo, Fukuda, Goto, Matsuki, Ohmura-Hoshino, Sada, Hotta, Yamamura, Inatome, Yanagi: "A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics." in: The EMBO journal, Vol. 25, Issue 15, pp. 3618-26, 2006 (PubMed).

Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).