|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Density-Regulated Protein (DENR) antibody
|Synonyms||DENR, DKFZp469K2322, denr, MGC84106, 1500003K04Rik, drp, drp1, smap-3, MGC79758, MGC107862, zgc:92629, zgc:113309, Denr, MGC138065, DRP, DRP1, SMAP-3|
Alternatives ELISA, Western Blotting (WB)
|5 references available|
|Price||450.00 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||DENR (NP_003668, 1 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K|
|Description||Other names: DRP, DRP1, SMAP3 density-regulated protein|
|Characteristics||Purified Mouse Monoclonal Antibody (Mab)|
|Specificity||DENR (NP_003668, 1 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Molecular Weight||22092 DA|
Background: This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.
|Application Notes||ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000|
|Buffer||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Translation Factors, Signaling, Cell Structure|
|Restrictions||For Research Use only|
Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).
Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).
Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).
Yonashiro, Ishido, Kyo et al.: "A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics." in: The EMBO journal, Vol. 25, Issue 15, pp. 3618-26, 2006 (PubMed).
Mazan-Mamczarz, Gartenhaus: "Post-transcriptional control of the MCT-1-associated protein DENR/DRP by RNA-binding protein AUF1." in: Cancer genomics & proteomics, Vol. 4, Issue 3, pp. 233-9, 2007 (PubMed).
|Reactivities||Human (5), Mouse (Murine) (4), Rat (Rattus) (4), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)|
|Applications||ELISA (5), Western Blotting (WB) (5), Immunofluorescence (IF) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)|