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Density-Regulated Protein (DENR) antibody

Details for Product No. ABIN394092
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Antigen
Synonyms
1500003K04Rik, DRP, DRP1, SMAP-3, DENR, DKFZp469K2322, denr, MGC84106, drp, drp1, smap-3, MGC79758, MGC107862, im:6891640, zgc:113309, zgc:92629, Denr, DDBDRAFT_0205981, DDBDRAFT_0266779, DDB_0205981, ... show more
1500003K04Rik, DRP, DRP1, SMAP-3, DENR, DKFZp469K2322, denr, MGC84106, drp, drp1, smap-3, MGC79758, MGC107862, im:6891640, zgc:113309, zgc:92629, Denr, DDBDRAFT_0205981, DDBDRAFT_0266779, DDB_0205981, DDB_0266779 show less
Reactivity
Human
(22), (3), (3)
Host
Mouse
(11), (11)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(21), (11), (3), (1), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN394092
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen DENR (NP_003668, 1 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1H3
Isotype IgG2a kappa
Specificity DENR (NP_003668, 1 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DENR
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22092 DA
Gene ID 12406
UniProt NP_003668
Research Area Translation Factors, Signaling, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Density-Regulated Protein (DENR) antibody Western Blot analysis of DENR expression in transfected 293T cell line by DENR monoclonal antibody (M01), clone 1H3. Lane 1: DENR transfected lysate(22.092 KDa). Lane 2: Non-transfected lysate. Western blot analysis of DENR over-expressed 293 cell line, cotransfected with DENR Validated Chimera RNAi used as specificity and loading control.
anti-Density-Regulated Protein (DENR) antibody (2) anti-Density-Regulated Protein (DENR) antibody (Image 2)
Background publications Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome...." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Yonashiro, Ishido, Kyo et al.: "A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics." in: The EMBO journal, Vol. 25, Issue 15, pp. 3618-26, 2006 (PubMed).

Mazan-Mamczarz, Gartenhaus: "Post-transcriptional control of the MCT-1-associated protein DENR/DRP by RNA-binding protein AUF1." in: Cancer genomics & proteomics, Vol. 4, Issue 3, pp. 233-9, 2007 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN394092
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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