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Details for Product No. ABIN394092

Density-Regulated Protein (DENR) antibody

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Antigen
Synonyms
1500003K04Rik, DRP, DRP1, SMAP-3, DENR, DKFZp469K2322, denr, MGC84106, drp, drp1, smap-3, MGC79758, MGC107862, im:6891640, zgc:113309, zgc:92629, Denr, DDBDRAFT_0205981, DDBDRAFT_0266779, DDB_0205981, ... show more
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN394092
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen DENR (NP_003668, 1 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1H3
Isotype IgG2a kappa
Specificity DENR (NP_003668, 1 a.a. ~ 82 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DENR
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 22092 DA
Gene ID 12406
UniProt NP_003668
Research Area Translation Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Yonashiro, Ishido, Kyo et al.: "A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics." in: The EMBO journal, Vol. 25, Issue 15, pp. 3618-26, 2006 (PubMed).

Mazan-Mamczarz, Gartenhaus: "Post-transcriptional control of the MCT-1-associated protein DENR/DRP by RNA-binding protein AUF1." in: Cancer genomics & proteomics, Vol. 4, Issue 3, pp. 233-9, 2007 (PubMed).

Alternatives for antigen "Density-Regulated Protein (DENR)", type "Antibodies"
Hosts (7), (4)
Reactivities (11), (2), (2)
Applications (11), (5), (2), (1), (1)
Epitopes (2), (2), (2), (1), (1)
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