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EIF4ENIF1 antibody (Eukaryotic Translation Initiation Factor 4E Nuclear Import Factor 1) (AA 886-986)

Details for Product anti-EIF4ENIF1 Antibody No. ABIN394130, Supplier: Login to see New
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Synonyms RGD1560908, eif4enif1, MGC80355, EIF4ENIF1, wu:fd15a05, zgc:101646, MGC147579, 4E-T, Clast4, 2610509L04Rik, A930019J01Rik, AA410001, AU021239, D11Ertd166e
AA 886-986
(23), (19), (15), (13), (6), (4), (2), (2), (2), (2), (1)
(87), (18), (18), (4), (4), (4), (1), (1), (1), (1)
(53), (20), (14)
Clonality (Clone)
Monoclonal ()
This EIF4ENIF1 antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(67), (42), (17), (11), (11), (9), (3), (3), (3), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen EIF4ENIF1 (NP_062817, 886 a.a. ~ 986 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2C4
Isotype IgG2a kappa
Specificity EIF4ENIF1 (NP_062817, 886 a.a. ~ 986 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name EIF4ENIF1 (EIF4ENIF1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 108201 DA
Gene ID 12406
NCBI Accession NP_062817
Research Area Translation Factors, Signaling, Cell Structure
Application Notes Western blot = 1:500-1000

Background: The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic, its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-EIF4ENIF1 antibody (Eukaryotic Translation Initiation Factor 4E Nuclear Import Factor 1) (AA 886-986) (ABIN394130) Western Blot analysis of EIF4ENIF1 expression in transfected 293T cell line by EIF4EN...
Background publications Suzuki, Minami, Suzuki et al.: "The Hsp90 inhibitor geldanamycin abrogates colocalization of eIF4E and eIF4E-transporter into stress granules and association of eIF4E with eIF4G." in: The Journal of biological chemistry, Vol. 284, Issue 51, pp. 35597-604, 2009 (PubMed).

Venkatesan, Rual, Vazquez et al.: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).

Lee, Cho, Kim: "Ectopic expression of eIF4E-transporter triggers the movement of eIF4E into P-bodies, inhibiting steady-state translation but not the pioneer round of translation." in: Biochemical and biophysical research communications, Vol. 369, Issue 4, pp. 1160-5, 2008 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Denoeud, Kapranov, Ucla et al.: "Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions." in: Genome research, Vol. 17, Issue 6, pp. 746-59, 2007 (PubMed).

Catalog No. ABIN394130
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