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SCAN Domain Containing 1 (SCAND1) (AA 1-180) antibody

Details for Product No. ABIN394158, Supplier: Login to see
Antigen
  • RAZ1
  • SDP1
Epitope
AA 1-180
17
15
4
3
2
2
1
1
1
1
1
Reactivity
Human
46
2
2
Host
Mouse
36
8
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
ELISA, Western Blotting (WB)
41
25
9
4
3
2
Supplier
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Immunogen SCAND1 (AAH36709, 1 a.a. ~ 180 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2F11
Isotype IgG2b kappa
Specificity SCAND1 (AAH36709, 1 a.a. ~ 180 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name SCAND1 (SCAND1 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 19082 DA
Gene ID 12406
Research Area Transcription Factors, Signaling, Cell Structure
Pathways
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. Functional studies have established that the SCAN box is a protein interaction domain that mediates both hetero- and homoprotein associations, and maybe involved in regulation of transcriptional activity. Two transcript variants with different 5' UTRs, but encoding the same protein, have been described for this gene.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-SCAN Domain Containing 1 (SCAND1) (AA 1-180) antibody (ABIN394158) Detection limit for recombinant GST tagged SCAND1 is approximately 0.1 ng/mL as a cap...
Background publications Lu, Dollé, Imholz et al.: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." in: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, 2008 (PubMed).

Carneiro, Silva, Alves et al.: "Spectroscopic characterization of the tumor antigen NY-REN-21 and identification of heterodimer formation with SCAND1." in: Biochemical and biophysical research communications, Vol. 343, Issue 1, pp. 260-8, 2006 (PubMed).

Mehrle, Rosenfelder, Schupp et al.: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, 2005 (PubMed).

Rual, Venkatesan, Hao et al.: "Towards a proteome-scale map of the human protein-protein interaction network. ..." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, 2005 (PubMed).

Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).