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Interleukin 20 (IL20) (AA 67-177) antibody

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Synonyms IL20, IL-20, IL10D, ZCYTO10, Zcyto10
AA 67-177
(24), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
(79), (19), (14)
(34), (27), (18), (1)
Clonality (Clone)
Monoclonal ()
(7), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(58), (32), (11), (8), (5), (4), (3), (3), (2), (2), (1), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen IL20 (NP_061194, 67 a.a. ~ 177 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 2H8
Isotype IgG1 kappa
Specificity IL20 (NP_061194, 67 a.a. ~ 177 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name IL20 (IL20 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 20072 DA
Gene ID 12406
NCBI Accession NP_061194
Research Area Transcription Factors, Signaling, Cell Structure
Application Notes Western blot = 1:500-1000

Background: The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Interleukin 20 (IL20) (AA 67-177) antibody (ABIN394201) IL20 monoclonal antibody (M01), clone 2H8 Western Blot analysis of IL20 expression in...
Immunohistochemistry (IHC) image for anti-Interleukin 20 (IL20) (AA 67-177) antibody (ABIN394201) anti-Interleukin 20 (IL20) (AA 67-177) antibody (Image 2)
Background publications Schuurhof, Bont, Siezen et al.: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

He, Liang: "IL-24 transgenic mice: in vivo evidence of overlapping functions for IL-20, IL-22, and IL-24 in the epidermis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 4, pp. 1793-8, 2010 (PubMed).

Wolk, Witte, Warszawska et al.: "The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis." in: European journal of immunology, Vol. 39, Issue 12, pp. 3570-81, 2009 (PubMed).

Novakova, Hubackova, Kosar et al.: "Cytokine expression and signaling in drug-induced cellular senescence." in: Oncogene, Vol. 29, Issue 2, pp. 273-84, 2010 (PubMed).

Catalog No. ABIN394201
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