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Homeobox Protein OTX1 (AA 10-117) antibody

Details for Product No. ABIN394209, Supplier: Log in to see
Antigen
  • A730044F23Rik
  • cb769
  • fj99f05
  • jv
  • otx1
  • otx1-A
  • OTX1X
  • wu:fj99f05
  • xotx1
  • zOtx1
Epitope
AA 10-117
18
14
11
5
5
4
4
2
2
2
2
1
1
Reactivity
Human
62
20
20
7
5
2
2
1
1
1
Host
Mouse
54
8
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
45
29
11
5
3
2
2
1
1
Supplier
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Immunogen OTX1 (NP_055377, 10 a.a. ~ 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3A5
Isotype IgG2a kappa
Specificity OTX1 (NP_055377, 10 a.a. ~ 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name OTX1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 37327 DA
Gene ID 12406
NCBI Accession NP_055377
Research Area Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Homeobox Protein OTX1 (AA 10-117) antibody (ABIN394209) Detection limit for recombinant GST tagged OTX1 is approximately 0.03 ng/mL as a capt...
Background publications Larsen, Lutterodt, Møllgård, Møller: "Expression of the homeobox genes OTX2 and OTX1 in the early developing human brain." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 58, Issue 7, pp. 669-78, 2010 (PubMed).

Omodei, Acampora, Russo, De Filippi, Severino, Di Francia, Frigeri, Mancuso, De Chiara, Pinto, Casola, Simeone: "Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma." in: The American journal of pathology, Vol. 175, Issue 6, pp. 2609-17, 2009 (PubMed).

Eeles, Kote-Jarai, Al Olama, Giles, Guy, Severi, Muir, Hopper, Henderson, Haiman, Schleutker, Hamdy, Neal, Donovan, Stanford, Ostrander, Ingles, John, Thibodeau, Schaid, Park, Spurdle, Clements et al.: "Identification of seven new prostate cancer susceptibility loci through a genome-wide association study." in: Nature genetics, Vol. 41, Issue 10, pp. 1116-21, 2009 (PubMed).

Xin, Rual, Hirozane-Kishikawa, Hill, Vidal, Boone, Thierry-Mieg: "Shifted Transversal Design smart-pooling for high coverage interactome mapping." in: Genome research, Vol. 19, Issue 7, pp. 1262-9, 2009 (PubMed).

Larsen, Lutterodt, Rath, Møller: "Expression of the homeobox genes PAX6, OTX2, and OTX1 in the early human fetal retina." in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, Vol. 27, Issue 5, pp. 485-92, 2009 (PubMed).