Homeobox Protein OTX1 antibody

Details for Product No. ABIN394209
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Antigen
Synonyms jv, A730044F23Rik, OTX1X, otx1, cb769, zOtx1, fj99f05, wu:fj99f05, otx1-A, xotx1
Reactivity
Human
(37), (19), (18), (17), (17), (12), (2), (2), (1), (1), (1), (1)
Host
Mouse
(30), (8)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(25), (12), (10), (4), (3), (2), (2), (1), (1)
Pubmed 5 references available
Catalog no. ABIN394209
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
Options
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen OTX1 (NP_055377, 10 a.a. ~ 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3A5
Isotype IgG2a kappa
Specificity OTX1 (NP_055377, 10 a.a. ~ 117 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name OTX1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 37327 DA
Gene ID 12406
UniProt NP_055377
Research Area Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Homeobox Protein OTX1 antibody Detection limit for recombinant GST tagged OTX1 is approximately 0.03 ng/mL as a capture antibody.
Background publications Larsen, Lutterodt, Rath et al.: "Expression of the homeobox genes PAX6, OTX2, and OTX1 in the early human fetal retina." in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, Vol. 27, Issue 5, pp. 485-92, 2009 (PubMed).

Xin, Rual, Hirozane-Kishikawa et al.: "Shifted Transversal Design smart-pooling for high coverage interactome mapping." in: Genome research, Vol. 19, Issue 7, pp. 1262-9, 2009 (PubMed).

Eeles, Kote-Jarai, Al Olama et al.: "Identification of seven new prostate cancer susceptibility loci through a genome-wide association study." in: Nature genetics, Vol. 41, Issue 10, pp. 1116-21, 2009 (PubMed).

Omodei, Acampora, Russo et al.: "Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma." in: The American journal of pathology, Vol. 175, Issue 6, pp. 2609-17, 2009 (PubMed).

Larsen, Lutterodt, Møllgård et al.: "Expression of the homeobox genes OTX2 and OTX1 in the early developing human brain." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 58, Issue 7, pp. 669-78, 2010 (PubMed).

Hosts (30), (8)
Reactivities (37), (19), (18), (17), (17), (12), (2), (2), (1), (1), (1), (1)
Applications (25), (12), (10), (4), (3), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (4), (4), (3), (2), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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