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Vitamin D-Binding Protein (GC) antibody

Details for Product No. ABIN394212
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Antigen
Synonyms DABP, DBP, DBP/GC, GRD3, VDBG, VDBP, Gc, DBP02, VDB, Vdbp, VTDB, zgc:110389, zgc:92753, GC
Reactivity
Human
(85), (27), (26), (17), (12), (6)
Host
Mouse
(59), (22), (13), (1), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(61), (55), (21), (13), (11), (10), (10), (3), (2), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
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Catalog No. ABIN394212
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen DBP (NP_001343, 226 a.a. ~ 326 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3A6
Isotype IgG1 kappa
Specificity DBP (NP_001343, 226 a.a. ~ 326 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DBP
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 34349 DA
Gene ID 12406
UniProt NP_001343
Research Area Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000
Comment

Background: DBP is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family (Khatib et al., 1994 [PubMed 7835883]).

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-Vitamin D-Binding Protein (GC) antibody Detection limit for recombinant GST tagged DBP is approximately 0.3 ng/mL as a capture antibody.
Background publications Lavebratt, Sjöholm, Partonen et al.: "PER2 variantion is associated with depression vulnerability." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 2, pp. 570-81, 2010 (PubMed).

Mansour, Talkowski, Wood et al.: "Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia." in: Bipolar disorders, Vol. 11, Issue 7, pp. 701-10, 2009 (PubMed).

Simon, Munger, Xing Yang et al.: "Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis." in: Multiple sclerosis (Houndmills, Basingstoke, England), Vol. 16, Issue 2, pp. 133-8, 2010 (PubMed).

Soria, Martínez-Amorós, Escaramís et al.: "Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 35, Issue 6, pp. 1279-89, 2010 (PubMed).

Utge, Soronen, Loukola et al.: "Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance." in: PLoS ONE, Vol. 5, Issue 2, pp. e9259, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN394212
450.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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