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Kruppel-Like Factor 6 (KLF6) (AA 1-101) antibody

Details for Product No. ABIN394239, Supplier: Log in to see
Antigen
  • gbf
  • zf9
  • bcd1
  • cba1
  • cpbp
  • pac1
  • st12
  • copeb
  • MGC53475
  • KLF6
  • MGC127307
  • BCD1
  • CBA1
  • COPEB
  • CPBP
  • GBF
  • PAC1
  • ST12
  • ZF9
  • AI448727
  • C86813
  • Copeb
  • FM2
  • FM6
  • Ierepo1
  • Ierepo3
  • R75280
  • Zf9
  • Aa1017
  • klf6
  • cb538
  • wu:fb76d04
  • wu:fb92h03
  • wu:fe26g06
  • wu:fk78f12
Epitope
AA 1-101
8
5
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
42
15
11
2
2
1
1
1
Host
Mouse
35
9
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
1
1
Application
ELISA
37
20
7
4
3
3
2
2
1
Supplier
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Immunogen KLF6 (NP_001291, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3C4
Isotype IgG1 kappa
Specificity KLF6 (NP_001291, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name KLF6 (KLF6 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 31865 DA
Gene ID 12406
NCBI Accession NP_001291
Research Area Translation Factors, Transcription Factors, Signaling, Cell Structure
Pathways
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-Kruppel-Like Factor 6 (KLF6) (AA 1-101) antibody (ABIN394239) Detection limit for recombinant GST tagged KLF6 is approximately 0.3 ng/mL as a captu...
Background publications Huh, Chen, Friedman et al.: "KLF6 Gene and early melanoma development in a collagen I-rich extracellular environment." in: Journal of the National Cancer Institute, Vol. 102, Issue 15, pp. 1131-47, 2010 (PubMed).

Liu, Wu, Chen et al.: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Gehrau, DAstolfo, Dumur et al.: "Nuclear expression of KLF6 tumor suppressor factor is highly associated with overexpression of ERBB2 oncoprotein in ductal breast carcinomas." in: PLoS ONE, Vol. 5, Issue 1, pp. e8929, 2010 (PubMed).

Lee, Ghiassi-Nejad, Paris et al.: "Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene." in: FEBS letters, Vol. 584, Issue 5, pp. 1006-10, 2010 (PubMed).