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Details for Product No. ABIN394239

Kruppel-Like Factor 6 (KLF6) antibody

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Antigen
Synonyms
BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9, FM2, FM6, Zf9, Copeb, C86813, R75280, Ierepo1, Ierepo3, AI448727, Aa1017, cb538, copeb, klf6, wu:fb76d04, wu:fb92h03, wu:fe26g06, wu:fk78f12, bcd1, cba1, ... show more
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA
Pubmed 5 references available
Catalog no. ABIN394239
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen KLF6 (NP_001291, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3C4
Isotype IgG1 kappa
Specificity KLF6 (NP_001291, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name KLF6
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 31865 DA
Gene ID 12406
UniProt NP_001291
Research Area Translation Factors, Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml
Comment

Background: This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Lee, Ghiassi-Nejad, Paris et al.: "Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene." in: FEBS letters, Vol. 584, Issue 5, pp. 1006-10, 2010 (PubMed).

Gehrau, DAstolfo, Dumur et al.: "Nuclear expression of KLF6 tumor suppressor factor is highly associated with overexpression of ERBB2 oncoprotein in ductal breast carcinomas." in: PLoS ONE, Vol. 5, Issue 1, pp. e8929, 2010 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Liu, Wu, Chen et al.: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, 2010 (PubMed).

Huh, Chen, Friedman et al.: "KLF6 Gene and early melanoma development in a collagen I-rich extracellular environment." in: Journal of the National Cancer Institute, Vol. 102, Issue 15, pp. 1131-47, 2010 (PubMed).

Alternatives for antigen "Kruppel-Like Factor 6 (KLF6)", type "Antibodies"
Hosts (31), (6)
Reactivities (37), (23), (19), (14), (13), (12), (1), (1)
Applications (25), (18), (10), (6), (5), (4), (3), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (5), (4), (2), (2), (2), (2), (1), (1), (1)
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