Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1) antibody

Antigen: Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1)

Synonyms: TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1, FLJ45380, ASPC, 1190006K01Rik, MGC187913, tug, aspl, asps, rcc17, ubxd9, aspcr1, ASPSCR1, MGC159635

Clonality: Monoclonal (3D10-1D11)

Host: Mouse

Reactivity: Human

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Certificates: ISO 9001:2008

Catalog no.: ABIN394251

Additional Information

Alternative name: ASPSCR1

Gene ID: 79058

Immunogen: ASPSCR1 (AAH18722, 1 a.a. ~ 554 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K

Isotype: IgG1 kappa

Clone: 3D10-1D11

Description: Other names: ASPCR1, ASPL, ASPS, RCC17, TUG alveolar soft part sarcoma chromosome region, candidate 1

Characteristics: Purified Mouse Monoclonal Antibody (Mab)

Specificity: ASPSCR1 (AAH18722, 1 a.a. ~ 554 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Molecular Weight: 60183 DA

Comments:

Background: This gene is a candidate gene for alveolar soft part sarcoma (ASPS). It has been found that this gene is fused with transcription factor TFE3 gene in ASPS and also in renal cell carcinomas. Several alternatively spliced transcript variants of this gene have been described, but their full length nature has not been determined.

Application Details

Application Notes: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml

Purification: Purified

Buffer: Clear, colorless solution in phosphate buffered saline, pH 7.2 .

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cancer, Transcription Factors, Signaling, Cell Structure

Restrictions: For Research Use only

Images

ASPSCR1 monoclonal antibody (M01), clone 3D10-1D11 Western Blot analysis of ASPSCR1 expression in Hela NE ( Cat # L013V3 ). Immunoperoxidase of monoclonal antibody to ASPSCR1 ( Cat # AT1219a ) on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3ug/ml]

anti-Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1) antibody (Image 2)

Publications

Product: Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Vistica, Krosky, Kenney et al.: "Immunohistochemical discrimination between the ASPL-TFE3 fusion proteins of alveolar soft part sarcoma." in: Journal of pediatric hematology/oncology, Vol. 30, Issue 1, pp. 46-52, 2008 (PubMed).

Alexandru, Graumann, Smith et al.: "UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover." in: Cell, Vol. 134, Issue 5, pp. 804-16, 2008 (PubMed).

Ban, Heo, Oh et al.: "Identification of type 2 diabetes-associated combination of SNPs using support vector machine." in: BMC genetics, Vol. 11, pp. 26, 2010 (PubMed).