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Details for Product No. ABIN394251

Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1) antibody

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Antigen
Synonyms ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9, ASPC, 1190006K01Rik, tug, aspl, asps, rcc17, ubxd9, aspcr1
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN394251
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen ASPSCR1 (AAH18722, 1 a.a. ~ 554 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D10-1D11
Isotype IgG1 kappa
Specificity ASPSCR1 (AAH18722, 1 a.a. ~ 554 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name ASPSCR1
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 60183 DA
Gene ID 12406
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml
Comment

Background: This gene is a candidate gene for alveolar soft part sarcoma (ASPS). It has been found that this gene is fused with transcription factor TFE3 gene in ASPS and also in renal cell carcinomas. Several alternatively spliced transcript variants of this gene have been described, but their full length nature has not been determined.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Vistica, Krosky, Kenney et al.: "Immunohistochemical discrimination between the ASPL-TFE3 fusion proteins of alveolar soft part sarcoma." in: Journal of pediatric hematology/oncology, Vol. 30, Issue 1, pp. 46-52, 2008 (PubMed).

Alexandru, Graumann, Smith et al.: "UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover." in: Cell, Vol. 134, Issue 5, pp. 804-16, 2008 (PubMed).

Ban, Heo, Oh et al.: "Identification of type 2 diabetes-associated combination of SNPs using support vector machine." in: BMC genetics, Vol. 11, pp. 26, 2010 (PubMed).

Alternatives for antigen "Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1)", type "Antibodies"
Hosts (15), (13)
Reactivities (18), (11)
Applications (26), (14), (3), (2), (2), (2), (2)
Epitopes (4), (4), (3), (2), (2), (2), (2), (1), (1), (1)
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