DDX6 antibody (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6) (AA 1-484)

Details for Product anti-DDX6 Antibody No. ABIN394255, Supplier: Log in to see
Antigen
  • si:ch211-147p17.1
  • P54H
  • Xp54
  • hlr2
  • me31b
  • p54
  • rck
  • HLR2
  • P54
  • RCK
  • p54h
  • RGD1564560
  • 1110001P04Rik
  • E230023J21Rik
  • mRCK/P54
  • DEAD (Asp-Glu-Ala-Asp) box helicase 6
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
  • DDX6
  • ddx6
  • Ddx6
Alternatives
anti-Human DDX6 antibody for Dot Blot
Epitope
AA 1-484
44
10
9
9
9
8
7
6
4
3
3
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
121
46
26
12
9
9
8
7
7
5
4
4
3
3
3
1
1
1
Host
Mouse
91
19
11
Clonality (Clone)
Monoclonal ()
Conjugate
This DDX6 antibody is un-conjugated
7
7
6
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
114
55
44
29
21
18
9
3
1
1
Options
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Immunogen DDX6 (AAH65007, 1 a.a. ~ 484 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D2
Isotype IgG1 kappa
Specificity DDX6 (AAH65007, 1 a.a. ~ 484 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DDX6 (DDX6 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 54417 DA
Gene ID 12406
Research Area Translation Factors, Signaling, Cell Structure
Pathways Ribonucleoprotein Complex Subunit Organization
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-DDX6 antibody (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6) (AA 1-484) (ABIN394255) Western Blot analysis of DDX6 expression in transfected 293T cell line by DDX6 monocl...
Immunohistochemistry (IHC) image for anti-DDX6 antibody (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6) (AA 1-484) (ABIN394255) anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (AA 1-484) antibody (Image 2)
Background publications Jangra, Yi, Lemon: "DDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation." in: Journal of virology, Vol. 84, Issue 13, pp. 6810-24, 2010 (PubMed).

Lind, Macgregor, Vink, Pergadia, Hansell, de Moor, Smit, Hottenga, Richter, Heath, Martin, Willemsen, de Geus, Vogelzangs, Penninx, Whitfield, Montgomery, Boomsma, Madden: "A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations." in: Twin research and human genetics : the official journal of the International Society for Twin Studies, Vol. 13, Issue 1, pp. 10-29, 2010 (PubMed).

Han, Zheng, Cui, Sun, Ye, Hu, Xu, Cai, Huang, Zhao, Xie, Fang, Lu, Xu, Li, Pan, Deng, Zeng, Ye, Zhang, Wang, Hao, Ma, Zuo, Zhou, Du, Cheng, Yang, Shen, Li, Sheng, Zuo, Zhu, Gao, Zhang, Guo, Li et al.: "Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus...." in: Nature genetics, Vol. 41, Issue 11, pp. 1234-7, 2009 (PubMed).

Minshall, Kress, Weil, Standart: "Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly." in: Molecular biology of the cell, Vol. 20, Issue 9, pp. 2464-72, 2009 (PubMed).

Tritschler, Braun, Eulalio, Truffault, Izaurralde, Weichenrieder: "Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B." in: Molecular cell, Vol. 33, Issue 5, pp. 661-8, 2009 (PubMed).