You are viewing an incomplete version of our website. Please click to reload the website as full version.

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (AA 1-484) antibody

Details for Product No. ABIN394255, Supplier: Log in to see
Antigen
  • si:ch211-147p17.1
  • P54H
  • Xp54
  • hlr2
  • me31b
  • p54
  • rck
  • HLR2
  • P54
  • RCK
  • p54h
  • RGD1564560
  • 1110001P04Rik
  • E230023J21Rik
  • mRCK/P54
Epitope
AA 1-484
35
16
15
13
9
6
5
3
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
96
19
17
6
3
2
1
1
1
1
Host
Mouse
71
15
10
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
6
5
5
5
5
5
Application
Western Blotting (WB)
89
53
25
10
6
5
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen DDX6 (AAH65007, 1 a.a. ~ 484 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D2
Isotype IgG1 kappa
Specificity DDX6 (AAH65007, 1 a.a. ~ 484 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DDX6 (DDX6 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 54417 DA
Gene ID 12406
Research Area Translation Factors, Signaling, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (AA 1-484) antibody (ABIN394255) Western Blot analysis of DDX6 expression in transfected 293T cell line by DDX6 monocl...
Immunohistochemistry (IHC) image for anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (AA 1-484) antibody (ABIN394255) anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) (AA 1-484) antibody (Image 2)
Background publications Jangra, Yi, Lemon: "DDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation." in: Journal of virology, Vol. 84, Issue 13, pp. 6810-24, 2010 (PubMed).

Lind, Macgregor, Vink et al.: "A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations." in: Twin research and human genetics : the official journal of the International Society for Twin Studies, Vol. 13, Issue 1, pp. 10-29, 2010 (PubMed).

Han, Zheng, Cui et al.: "Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus...." in: Nature genetics, Vol. 41, Issue 11, pp. 1234-7, 2009 (PubMed).

Minshall, Kress, Weil et al.: "Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly." in: Molecular biology of the cell, Vol. 20, Issue 9, pp. 2464-72, 2009 (PubMed).

Tritschler, Braun, Eulalio et al.: "Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B." in: Molecular cell, Vol. 33, Issue 5, pp. 661-8, 2009 (PubMed).