Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN394255

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms HLR2, P54, RCK, RGD1564560, 1110001P04Rik, E230023J21Rik, mRCK/P54, p54, rck, p54h, si:ch211-147p17.1, P54H, Xp54, hlr2, me31b
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN394255
Quantity 0.1 mg
Price
450.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen DDX6 (AAH65007, 1 a.a. ~ 484 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D2
Isotype IgG1 kappa
Specificity DDX6 (AAH65007, 1 a.a. ~ 484 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name DDX6
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 54417 DA
Gene ID 12406
Research Area Translation Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000 Immunohistochemistry ~~ 1.5ug/ml
Comment

Background: This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.

Restrictions For Research Use only
Concentration 1 mg/ml
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Tritschler, Braun, Eulalio et al.: "Structural basis for the mutually exclusive anchoring of P body components EDC3 and Tral to the DEAD box protein DDX6/Me31B." in: Molecular cell, Vol. 33, Issue 5, pp. 661-8, 2009 (PubMed).

Minshall, Kress, Weil et al.: "Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly." in: Molecular biology of the cell, Vol. 20, Issue 9, pp. 2464-72, 2009 (PubMed).

Han, Zheng, Cui et al.: "Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus." in: Nature genetics, Vol. 41, Issue 11, pp. 1234-7, 2009 (PubMed).

Lind, Macgregor, Vink et al.: "A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations." in: Twin research and human genetics : the official journal of the International Society for Twin Studies, Vol. 13, Issue 1, pp. 10-29, 2010 (PubMed).

Jangra, Yi, Lemon: "DDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation." in: Journal of virology, Vol. 84, Issue 13, pp. 6810-24, 2010 (PubMed).

Alternatives for antigen "DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6 (DDX6)", type "Antibodies"
Hosts (25), (6), (2)
Reactivities (30), (6), (5), (3), (1), (1), (1)
Applications (32), (9), (6), (5), (5), (1), (1), (1)
Epitopes (9), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Beacon