TATA Box Binding Protein Associated Factor 11 (TAF11) (AA 158-211) antibody

Details for Product No. ABIN394257
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Antigen
Synonyms 1110038O14Rik, 28kDa, AI115401, AL024207, AW552398, PRO214, TAF2I, TAFII28, MGC:15243
Epitope
AA 158-211
(10), (9), (8), (6), (2)
Reactivity
Human
(32), (2)
Host
Mouse
(20), (12)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunofluorescence (IF), Western Blotting (WB)
(32), (22), (12), (8), (6), (6), (2)
Pubmed 5 references available
Quantity 0.1 mg
Options
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Catalog No. ABIN394257
450.00 $
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Immunogen TAF11 (NP_005634, 158 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3D3
Isotype IgG1 kappa
Specificity TAF11 (NP_005634, 158 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name TAF11
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 23307 DA
Gene ID 12406
NCBI Accession NP_005634
Research Area Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes Western blot = 1:500-1000
Comment

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
anti-TATA Box Binding Protein Associated Factor 11 (TAF11) (AA 158-211) antibody Immunofluorescence of monoclonal antibody to TAF11 on HeLa cell (antibody concentration 10 µg/mL). TAF11 monoclonal antibody (M01), clone 3D3 Western Blot analysis of TAF11 expression in Hela NE.
anti-TATA Box Binding Protein Associated Factor 11 (TAF11) (AA 158-211) antibody (2) anti-TATA Box Binding Protein Associated Factor 11 (TAF11) (AA 158-211) antibody (Image 2)
Background publications Mengus, Gangloff, Carré et al.: "The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10064-71, 2000 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Guermah, Ge, Chiang et al.: "The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis." in: Molecular cell, Vol. 12, Issue 4, pp. 991-1001, 2003 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Validation Images
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