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GTF3A antibody (General Transcription Factor IIIA) (AA 185-275)

Details for Product anti-GTF3A Antibody No. ABIN394291, Supplier: Login to see New
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Synonyms GTF3A, gtf3a, TFIIIA, zgc:111799, 2010015D03Rik, 2610111I01Rik, 5330403M05Rik, AP2
AA 185-275
(16), (15), (9), (6), (3), (2), (1), (1), (1)
(39), (1), (1), (1)
(28), (12)
Clonality (Clone)
Monoclonal ()
This GTF3A antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
(34), (31), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 8 to 11 Business Days
Immunogen GTF3A (NP_002088, 185 a.a. ~ 275 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 3F7
Isotype IgG2b kappa
Specificity GTF3A (NP_002088, 185 a.a. ~ 275 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Alternative Name GTF3A (GTF3A Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 41515 DA
Gene ID 12406
NCBI Accession NP_002088
Research Area Translation Factors, Transcription Factors, Signaling, Cell Structure
Application Notes ELISA ~~ 1ug/ml~3ng/ml

Background: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.

Restrictions For Research Use only
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
ELISA image for anti-GTF3A antibody (General Transcription Factor IIIA) (AA 185-275) (ABIN394291) Detection limit for recombinant GST tagged GTF3A is approximately 0.3 ng/mL as a capt...
Background publications Varghese, Barriere, Carbone et al.: "Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway." in: Molecular and cellular biology, Vol. 28, Issue 17, pp. 5275-87, 2008 (PubMed).

Barbe, Lundberg, Oksvold et al.: "Toward a confocal subcellular atlas of the human proteome." in: Molecular & cellular proteomics : MCP, Vol. 7, Issue 3, pp. 499-508, 2008 (PubMed).

Newton-Cheh, Guo, Wang et al.: "Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study." in: BMC medical genetics, Vol. 8 Suppl 1, pp. S7, 2007 (PubMed).

Wu, Ma, Brown et al.: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, 2007 (PubMed).

Tsang, Connell, Brown et al.: "A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex." in: Genomics, Vol. 88, Issue 3, pp. 333-46, 2006 (PubMed).

Catalog No. ABIN394291
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